Ulcon: Chemical Formula, Presentation, Dosage, Indications, Precautions, Side Effects and Interactions

Sucralfate is also used to prevent and treat gastric symptoms produced by the use of non-steroidal anti-inflammatory drugs.

Ulcon or sucralfate is an orally active drug, prescribed for the treatment and prevention of duodenal ulcers, the relief of gastroesophageal reflux , in the prophylaxis of stress ulcers and as maintenance therapy.

The therapeutic activity of sucralfate is very similar to that of cimetidine.

Chemical formula

  • Formula: C12H54Al16O75S8.
  • Sucralfate: Basic salt of aluminum sulfate acid of sucrose.

Presentations of the Ulcon

  • Tablets
  • Suspension.


Tablets:  Ulcon tablets are recommended with a stronger initial dose and two (02) tablets are prescribed two (02) times a day, administered one (01) hour before each meal.

And a maintenance dose where one (01) tablet is prescribed, two (02) times a day, administering it one (01) hour before each meal.

Suspension. The recommended initial dose of Ulcon in suspension is to take ten (10) ml, two (02) times a day, one (01) hour before meals.

And a maintenance dose, where they are prescribed five (05) ml, two (02) times per day, one (01) hour before meals.

Mechanism of action

The Ulcon or sucralfate acts by creating a barrier over the ulcer. When the Ulcon is in an acid medium, it produces a viscous substance that binds to the proteins present in the ulcer lesion.

This protects it from the acidic action of the gastric juices and prevents the mucosa from continuing to be damaged, in order to help the ulcers heal more quickly.

Ulcon indications

The Ulcon has as active ingredient sucrafalto, this is a protector of the gastric mucosa in cases of gastroesophageal reflux, gastritis , gastroduodenal ulcer and maintenance therapy.

Treat and prevent stomach ulcers as well as prevent new ulcers from forming by the use of medications such as nonsteroidal anti-inflammatory drugs ( naproxen , ibuprofen) and the use of aspirin.

Precautions and contraindications

The Ulcon or sucralfate, is a product whose use is restricted in children under 14 years.

It is also restricted during pregnancy or during breastfeeding, since there are no specific studies in children or their effect on the fetus or breast milk.

Its use is not restricted in patients with compromised renal function and is prohibited in patients with uremia and with dialysis treatment.

Within the components of this medicine is aluminum, which under normal conditions is eliminated by the kidneys.

So people with kidney difficulties, may have a higher risk of high levels in the body due to problems to be eliminated by the kidneys.

There is a wide range of medications that have not been specifically tested in the elderly.

Therefore, it is possible that it is ignored if they work in exactly the same way in this age group as in young adults.

In view of the fact that renal function decreases with age, and that there are no specific studies that report the safety of the drug in geriatric patients. It is necessary to verify the state of renal function before administering this medicine.

The use of Ulcon or sucralfate is not recommended in patients with pathologies such as:

  • Difficulties in swallowing as swallowing problems and history of having required aspiration.
  • Intestinal and stomach problems such as delayed gastric emptying, with prescription for the use of a tube for feeding.
  • Use of a respiratory tube or tracheotomy.
  • Risk of bezoar formation (especially in patients in intensive care) and encephalopathy.
  • Patients who have an allergy to the components that suffer from another allergy.

Side effects

Among the side effects that can occur with the use of Ulcon or sucralfate are:

  • Constipation.
  • Vertigo.
  • Dermal eruptions.
  • Itching and inflammation especially on the face, tongue and throat.
  • Intense dizziness
  • Difficulty breathing.
  • Gastrointestinal minor disorders such as unusual and persistent feeling of stomach fullness, vomiting, stomach pain, especially after meals, difficulty swallowing, constipation, dry mouth sensation, upset stomach, flatulence and nausea.

Although these symptoms are of little importance and intensity, in case they become more acute or in case of persisting, it is necessary to suspend its use and go to the treating doctor.

Interactions of Ulcon with other medications

Within the interactions with other medications it is possible that problems may arise with the use of:

  • Quenodeoxicólico acid.
  • Ursodeoxycholic acid.
  • Amfotericina B.
  • Colistin
  • Digoxin
  • Phenytoin
  • Ketoconazole
  • Evotiroxina.
  • Ranitidine.

In some cases the absorption of aluminum increases with drugs that have in their components hydrogen and sodium or potassium citrate.

It should be administered two hours later when there is concomitant treatment with ofloxacin, norfloxacin and fluoroquinolones.

Special caution should be exercised with the use of oral anticoagulants such as warfarin.

Other pathologies

In the case of patients who have other pathologies, they may be affected with the use of this medicine:

  • In the presence of diseases that cause obstruction of the gastrointestinal tract: Ulcon or sucralfate can bind to other foods and drugs ingested and cause obstruction of the gastrointestinal tract.
  • Renal impairment : A toxic increase in the levels of aluminum in the blood flow can be caused by its use.