Betagen: Uses, Benefits, Mechanism, Precautions, Administration, Side Effects and Contraindications

It is a topical spray used on dogs to treat infected superficial lesions caused by bacteria.

It contains gentamicin, an antibiotic, and betamethasone (an anti-inflammatory).

Betagen is an antimicrobial and corticosteroid combination used in dogs to treat superficial lesions caused by susceptible bacteria.

Betagen Topical Spray can also be used for purposes other than those listed. This medication requires a prescription from your veterinarian.


  • Ideal for hot spots and skin rashes.
  • It can speed up the healing of skin infections.
  • Effective treatment for dogs with sensitive skin and allergies.
  • Customers are raving about how easy it is to use.

How does the Betagen Topical Spray work?

Betagen is a combination of an antibiotic to treat bacterial infections and a corticosteroid to treat any accompanying inflammation or itching.


Betagen should not be used for more than seven days unless instructed otherwise by your veterinarian. Do not use it if your pet has a viral or fungal infection. Inform your veterinarian if your pet is pregnant or nursing.

Generic name

Gentamicin sulfate with betamethasone valerate topical spray.


What is the most important thing I should know about Betagen Topical Spray?

Betagen Topical Spray is a prescription drug approved by the FDA for veterinary use in dogs. The Betagen Topical Spray is available in a 120 ml plastic spray bottle.

Each ml contains gentamicin sulfate equivalent to 0.57 mg of gentamicin base and betamethasone valerate equivalent to 0.284 mg of betamethasone.

What should I discuss with my vet before using Betagen on my pet?

Do not use Betagen if your pet has a viral or fungal infection. Inform your veterinarian if your pet is pregnant or nursing.

How should Betagen be used?

Use this medicine as prescribed by your veterinarian. If you do not understand the instructions, ask the pharmacist or veterinarian to explain them. The usual dose for dogs is two sprays administered 2 to 4 times a day for seven days.

Keep the spray bottle upright and apply 3-6 inches from the affected area. Store Betagen Topical Spray at room temperature, away from moisture and heat. Keep out of the reach of pets or children.

What are the possible side effects of Betagen?

There should be no severe side effects. Long-term use of this medicine can lead to the overgrowth of non-susceptible organisms such as fungi and yeast.

Weight loss, increased thirst and urination, vomiting, and diarrhea have occurred in animals after synthetic corticosteroids.

Stick with the medication and talk to your trusted vet about any side effects that show out of the ordinary or seem bothersome to your pet.

What happens if I forget to apply a dose of Betagen Topical Spray?

Apply the missed dose as soon as possible. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not apply a double dose of the medicine.

What happens if there is an overdose of Betagen Topical Spray in the pet?

An overdose of this drug is unlikely. If an overdose is suspected, seek emergency veterinary medical treatment.

What should I avoid when using Betagen Topical Spray on my pet?

Do not use this medication on pets allergic to it or any individual ingredients. Treatment beyond seven days can lead to prolonged wound healing.

What other drugs will affect Betagen Topical Spray?

Before using the Betagen Topical Spray, inform your veterinarian if your pet uses other antibiotic or corticosteroid medications topically or orally. Talk to your vet or pharmacist before giving any prescription or over-the-counter medications.

Active ingredients (per ml)

  • Gentamicin sulfate: 0.57 mg.
  • Betamethasone Valerate: 0.284 mg.
  • Alcohol Isopropilo: 163 mg.
  • Propylene glycol.
  • Methylparaben (a preservative).
  • Propylparaben (a preservative).
  • Purified water.

Hydrochloric acid can be added to adjust the pH.


If hypersensitivity to any components occurs, treatment with this product should be discontinued and appropriate therapy instituted.

How to dispose of the product?

Do not flush drugs down the toilet or pour them down a drain unless instructed. Dispose of this product properly when it has expired or is no longer needed.

Consult your pharmacist or local waste disposal company for information on how to dispose of your product safely.