Rogastril: Description, Mechanism of Action, Pharmacology, Benefits, Dosage, Side Effects and Interactions

It is a substituted benzamide used for its prokinetic properties in treating gastroparesis and gastroesophageal reflux disease.

Antacids are the oldest and best-known medicines for treating heartburn; they have remained popular because they are fast-acting, inexpensive, available without a prescription, and safe for most people when used as directed.

Rogastril treats motility-related gastrointestinal disorders such as indigestion ( dyspepsia ), gastroesophageal reflux (frequent, persistent heartburn, flow of bitter fluid in the mouth, difficulty swallowing, and upper abdominal pain), delayed gastric emptying, and vomiting.

Rogastril treats functional dyspepsia, delayed gastric emptying, and other conditions. Rogastril may also be used for purposes not listed in this medication guide.

Rogastril contains Cinitapride as an active ingredient. Rogastril works by acting as an agonist at the serotonergic 5HT4 receptor and as an antagonist at the 5HT2 serotonergic and D2 dopamine receptors.


Rogastril is a gastroprokinetic agent and antiulcer agent of the benzamide class marketed in Spain and Mexico. It acts as an agonist of 5-HT1 and 5-HT4 receptors and an antagonist of 5-HT2 receptors.

Rogastril neutralizes acids in the stomach. You can take it to treat heartburn that has already started. If you ate a spicy dinner and have heartburn symptoms, Rogastril is probably your best option to put out that fire.


Mechanism of action and pharmacology

Heartburn can be a nuisance, especially after eating. That burning sensation that begins in the chest to the throat can be painful, not to mention uncomfortable, especially when stomach problems are included.

Using Rogastril for heartburn can be a great relief as it can reduce the production of acid in the stomach and thus eliminate the burning sensation in the chest area.

Rogastril improves the patient’s condition by performing the following functions:

  • It acts as an agonist at the serotonergic 5HT4 receptor and an antagonist at the 5HT2 serotonin and dopaminergic D2 receptors.
  • They can provide quick relief from heartburn as they are formulated to reduce the acid present in the stomach. These do not usually heal damage related to the esophagus, so heartburn is possible.
  • You can buy this over the counter with its effects that last longer than other antacids. However, the results may take a while before you can feel them.
  • It can block acid production and can also heal the lining of the esophagus. This may require a prescription from your doctor to get the correct dose.

Who needs Rogastril for heartburn?

You are probably wondering who can use the best heartburn medicine. If you feel that burning sensation from something you ate in your chest, you may be suffering from heartburn.

This can go away in a few seconds or last more than a minute or two. You can quickly eliminate this feeling by taking Rogastril to help reduce gas build-up in your stomach. There will be less stomach acid backing up into your esophagus.

If you have been diagnosed with acid reflux, Rogastril for heartburn can help you deal with the pain. Acid reflux can be triggered by inflammatory foods like spicy foods, alcohol, and the like.

When these foods are ingested, they can cause a build-up of gas in the stomach that can cause excess acid to form. This can lead to bloating, stomach aches, and heartburn.

Rogastril for heartburn can reduce incidents of heartburn and prevent the formation of acid in the stomach.

You can also use Rogastril for heartburn if you have gastroesophageal reflux disease. Although this is a more robust digestive problem, taking heartburn medication can lessen the burning sensation you feel. In this way, you will be able to function 100%.

What are the benefits of taking Rogastril?

There are several benefits of taking Rogastril for heartburn, especially when you experience a burning sensation in your chest or even the taste of bile in the back of your throat.

Heartburn can be triggered by acid reflux and can occur when you eat something that causes too much acid to form in your stomach.

Or due to a pre-existing condition. With that said, these are the benefits you can reap when you take this drug.

You can control heartburn: If you know that eating certain foods can cause heartburn, you can take Rogastril for a few minutes before eating to neutralize the acid build-up.

This way, you won’t have to worry about dealing with that burning sensation in your chest.

Helps heal the esophageal lining: When the acid returns to the esophagus, it is guaranteed that the lining of the esophagus will be damaged in the process. This way, you will feel less pain because the damage is being repaired.

Reduces Damage During Reflux: Rogastril for heartburn can also help minimize the damage that occurs in the body when acid reflux occurs.

Less erosion occurs when using heartburn medications as recommended by a specialist because you regulate the amount of acid present in the stomach.

Provides Relief – Another benefit of using Rogastril is that it can give you immediate relief once you feel that burning sensation that starts in your stomach and slowly works its way up to your esophagus.

Minimize Gas and Bloating – Since Rogastril is designed to break up or prevent acid from forming in your stomach, you will no longer have to deal with gas and bloating. In this way, there are stomach pain and cramps that bother you.

Dose of Rogastril

This product (Rogastril) is highly recommended by doctors, pharmacists, and gastroenterologists for those who often experience heartburn. Taking one pill a day of Rogastril can give you zero heartburn in 24 hours.

The presentations are in tablets and syrup. Tablets take longer to work and are not as strong as syrup, but many people find tablets more convenient. For faster relief, chew well before swallowing.

They can begin to relieve your symptoms in as little as 5 minutes. Relief can last as little as half an hour or up to 3 hours. Antacids will not prevent future heartburn attacks or heal any damage to the esophagus.

You need to follow the directions to get the most out of your heartburn medication (Rogastril) to experience relief in no time.

If you are the type of person who often experiences heartburn, this medication is worth using. It will take 1 to 4 days to get the desired effect.

If your heartburn is mild and due to something you ate, Rogastril is probably your best option. It will work quickly, and there is little downside.

But if your heartburn is more severe or occurs more than twice a week, you may need a more potent dose of Rogastril.

Rogastril side effects

Now that you have an idea of ​​the many benefits of taking Rogastril for heartburn, chances are you are eager to get it for your needs.

Your side effects may depend on how much you take and how often you take them. If you only take them once in a while, you may not have any. But some people using Rogastril may have stomach upsets.

If you have heart or kidney problems, you should talk to your doctor before taking them. However, first, there are some precautions that you should take into account:

For starters, Rogastril cannot be used to treat gastroesophageal reflux disease. They provide immediate relief, especially to those experiencing mild cases of heartburn.

The following is a list of possible side effects from all the ingredients that make up Rogastril.

Vomiting, nausea, diarrhea, drowsiness, headache, jaundice, loss of appetite, muscle pain, and joint pain. Rogastril can also cause side effects not mentioned here.

See your doctor if you have gastrointestinal bleeding, obstruction, perforation, or movement disorder. Do not drink alcohol. It can cause movement disorders or prolong the heartbeat in elderly patients.

Risk of cardiac arrhythmias, be careful if you are allergic to it; take this medicine at least 15 minutes before meals.


If you take other medicines or over-the-counter products simultaneously, the effects of Rogastril may change. Rogastril may interact with the following medications and products:

Anticholinergic agents and digoxin.


Hypersensitivity to Rogastril is a contraindication. Also, Rogastril should not be used if you have the following conditions: Hypersensitivity.

Measures to combine with the medicine

There are a variety of measures that people can take for heartburn symptoms. However, it is essential to speak with a doctor about the best solution for you.

Simple remedies to relieve heartburn include the following:

Quit Smoking – Quit smoking and avoid secondhand smoke.

Consider Prescription Medications – People with heartburn should also discuss using prescription medications with their doctor and whether they are appropriate for the individual.

Manage Body Weight – Overweight or obese people may find that reducing body weight can help. A diet and exercise weight loss program can help reduce acid reflux symptoms.

However, each person reacts to these changes differently, so it is essential to speak with a healthcare provider before losing too much weight.

Raise the head of the bed – You can allow gravity to reduce heartburn symptoms. Placing blocks under the top bed posts that raise the bed 6 to 8 inches can work.

Another option is to insert foam wedges between the mattress and the box spring to raise the angle of the head of the bed.

Use herbal preparations: Certain herbal preparations can also be helpful. Chamomile is an herb that can reduce the symptoms of gastroesophageal reflux disease.

Before starting any herbal supplement, people need to discuss possible side effects and drug interactions with their doctor.

Relax – Stress and tension can cause a wide range of unwanted side effects, including heartburn. Relaxation techniques, such as progressive muscle relaxation, meditation, or yoga, may alleviate some symptoms.

Make Some Simple Diet Changes – Specific dietary triggers can affect the onset and severity of heartburn.

People with heartburn should avoid the following foods:

  • Spicy or fatty foods, caffeinated drinks, tomato products, garlic, mint, alcohol, and carbonated beverages.

People should sit upright for 3 hours or more after a meal to reduce heartburn symptoms. People should also eat smaller meals and avoid eating in the 2 to 3 hours before sleeping.