Index
It is an antidepressant belonging to a group of medicines called selective serotonin reuptake inhibitors (SSRIs).
It is mainly used to treat depression.
Indications of Procimax
An indication is a term used primarily to know the list of conditions or symptoms or diseases for which the patient uses the medication.
A prevalent example is the case of paracetamol, it is frequently used for symptoms such as fever, or the doctor sometimes prescribes it for a headache or pains in the body.
A patient must know the indications of the medicines used for common ailments. They can be ingested without a prescription in the pharmacy, which means that the doctor can not prescribe the medication. Deanxit is also prescribed to treat mild and moderate anxiety and depression in people with or without psychosomatic symptoms.
Proxima (citalopram HBr) is indicated for the treatment of depression. The efficacy of Procimax in the treatment of depression was established in controlled trials of 4 to 6 weeks in outpatients whose diagnosis corresponded more closely to the category DSM-III and DSM-III-R of major depressive disorder.
A major depressive episode (DSM-IV) involves a prominent and relatively persistent depressive state (almost every day for at least two weeks) depressed or dysphoric, which usually interferes with daily functioning and includes at least five of the following symptoms:
- Depressed mood and loss of interest in usual activities.
- Significant weight changes and appetite, insomnia, or hypersomnia.
- Agitation or psychomotor retardation.
- Increase in fatigue.
- Feelings of guilt or uselessness.
- Altered concentration
- The attempt of suicide or suicidal ideation.
On the other hand, it is necessary that diagnosing major depression is confirmed. It is primary since depression is sometimes the result of different conditions such as chronic diseases and disorders such as cancer and AIDS.
It is essential to treat this type of disorder since depression interferes and causes clinically significant discomfort in various areas of the person’s daily functioning (social area, work area, academic area, among others).
The antidepressant action of Procimax in depressed hospitalized patients has not been adequately studied. The efficacy of Procimax was seen in the maintenance of an antidepressant response for up to 24 weeks after 6 to 8 weeks of acute treatment; this was demonstrated in two placebo-controlled trials.
However, the physician who chooses to use Procimax for prolonged periods must periodically re-evaluate the long-term usefulness of the medication for the individual patient.
Administration
- Use Procimax as directed by your doctor. You must check the medication label to see the exact dosage rules and have the correct use of Procimax.
- Promax comes with an additional information sheet called a medication guide for the patient. Could you read it carefully? Reread it each time you retake Procimax.
- Take Procimax orally with or without food.
- Use a marked measuring device for dosing medications.
- Ask your pharmacist for help if you are unsure how to measure your dose.
- Taking Procimax simultaneously every day will help you remember to take it.
Do not stop taking Procimax suddenly without consulting your doctor. You may have a higher risk of side effects (for example, mental or mood changes, numbness or tingling of the skin, dizziness, confusion, headache, trouble sleeping, and unusual tiredness).
If you need to stop Procimax, your doctor may gradually direct you to decrease your dose.
Continue to take Procimax even if you feel well.
The patient should not forget to take a dose. If this is the case, it is best to take it as soon as possible. However, if the time of the next dose is approaching, you must skip the previous one.
However, it is essential that you return to your daily dose schedule and that these omissions do not become frequent. You should not take two doses at a time.
Ask your healthcare provider any questions about the Procimax administration instructions.
Specific uses of Procimax
There are specific and general uses of a drug or medication. Medication is used to treat a disease; it is also used for proper prevention.
It can be used to cure specific symptoms of some conditions. The administration of these drugs depends on how the individual takes them. Its usefulness is more beneficial either by injections or tablets in some cases.
Finally, the medication can be used for problematic symptoms or cause emergencies since they can be life-threatening.
There are medications whose use can be suspended after several days in some cases. However, the application of other medicines must be continued for a prolonged period to obtain the appropriate benefits.
Adequate dose
The dose is defined as the amount that an individual must take according to the indication of a doctor or specialist in the condition that is suffered. The periods indicated by the doctor must be met and must not be exceeded in terms of the prescribed amount.
The dose can be expressed in mg for tablets or gm, sometimes in micro gm. For syrups or drops for infant syrups, it is expressed in ml. The dose depends on the condition or on the illness that is suffered. On the other hand, we must also consider the patient’s age.
Description of Procimax
Promax hydrobromide belongs to a class of antidepressant agents known as selective serotonin reuptake inhibitors (SSRIs). Promax and its N-demethylated metabolites exist as a racemic mixture, but their effects are mainly due to the S-enantiomer and S-citalopram.
Despite the distinct structural differences between compounds of this class, SSRIs possess a similar pharmacological activity. As with other antidepressant agents, several weeks of treatment may be required before a clinical effect is observed.
SSRIs are potent inhibitors of neuronal reuptake of serotonin. They have little or no effect on the reuptake of norepinephrine or dopamine and do not antagonize α- or β-adrenergic receptors, dopamine D2, or histamine H1.
SSRIs block the reuptake of serotonin during acute use and increase serotonin stimulation of somatodendritic 5-HT1A and terminal autoreceptors. Chronic use leads to the desensitization of somatodendritic 5-HT1A and terminal autoreceptors.
It is believed that the general clinical effect of increased mood and decreased anxiety is due to adaptive changes in neuronal function that lead to better serotonergic neurotransmission.
Side effects include dry mouth, nausea, dizziness, drowsiness, sexual dysfunction, and headache.
Side effects usually occur within the first two weeks of treatment and are less severe and frequent than those seen with tricyclic antidepressants.
Proxima is approved for the treatment of depression. Unlabeled indications include mild agitation associated with dementia in non-psychotic patients, smoking cessation, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy. Promax has the lowest pharmacological interaction of SSRIs.
Side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Procimax:
- Skin rash or urticaria.
- Hard breathing
- Swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as:
- Changes in mood or behavior, anxiety, panic attacks, trouble sleeping or feeling impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor immediately if you have:
- Blurred vision, tunnel vision, eye pain or swelling, or seeing halos around the lights.
- Headache with chest pain and severe dizziness, fainting, fast or strong heartbeat.
The severe reaction of the nervous system:
- Muscles are very rigid (rigid).
- High fever.
- Sweating
- Confusion.
- Fast or uneven heartbeat.
- Tremors
- The sensation that could faint.
Elevated levels of serotonin in the body:
- Agitation and hallucinations.
- Fever.
- Rapid heart rate
- Hyperactive reflexes.
- Nausea and vomiting.
- Diarrhea.
- Loss of coordination or fainting.
Or low levels of sodium in the body:
- Headache.
- Confusion.
- Difficulty speaking.
- Severe weakness
- Vomiting
- The sensation of instability.
Common side effects of Procimax may include:
- Drowsiness, dizziness, weakness.
- Anxiety, the feeling of instability, trouble sleeping (insomnia).
- Changes in vision
- Nausea, loss of appetite, diarrhea, constipation.
- Dry mouth, yawning.
- Cold symptoms include a stuffy nose, sneezing, sore throat, and cough.
- There may be excessive sweating.
- Weight changes
- Decreased sexual desire and sometimes impotence or difficulty in having an orgasm may occur.
Precautions about pregnancy
Pregnancy should be considered when prescribing medication as it is always a unique situation in which side effects may vary due to this condition.
Mainly, not only must be taken into account the hormonal changes that the metabolite differs in women but by the changes concerning the baby, since these changes also pass to the fetus and show their action there.
Care must be taken, the patient must be attentive, and the doctor must supervise the medication use during pregnancy. This supervision is mandatory.
Studies in animals have revealed evidence of embryo-fetal toxicity and effects on postnatal development, including teratogenicity, at doses higher than therapeutic doses in humans, which were also toxic to the mother.
There are no controlled data on human pregnancy. With more than 2,500 results exposed, the data published on pregnant women indicates no malformative fetal/neonatal toxicity.
A prospective comparative study (n = 396 pregnant women) indicates that the use of Procimax during embryogenesis is not associated with an apparent increased teratogenic risk in humans; however, spontaneous abortion in humans was reported.
Neonates exposed to SSRIs at the end of the third trimester have infrequent clinical findings that include respiratory distress, cyanosis, apnea, seizures, temperature instability, difficulty feeding, vomiting, hypoglycemia, hypotonia, hypertonia, hyperreflexia, tremors, and irritability.
These effects have occurred mainly at birth or a few days after delivery.
