Digoxin: Uses, Mechanism of Action, Precautions, Instructions and Contraindications

It is used to treat heart failure and irregular heartbeats. It should be started at lower doses and gradually increased.

It is necessary to closely monitor blood pressure and heart rate. Check the electrolyte level before starting treatment.

Congestive heart failure

Digoxin is used in the treatment of congestive heart failure, which is a type of heart disease, characterized by thickening of the walls of the left ventricle.

Atrial fibrillation

Digoxin is used in the treatment of atrial fibrillation, which is a type of heart disease characterized by irregular heartbeats and leads to decreased blood flow.

Digoxin tablets are used in the treatment of heart failure in adults, Treatment of atrial fibrillation in adults and other conditions. Digoxin tablets may also be used for purposes not listed in this medication guide.

Digoxin tablets work by increasing the availability of intracellular calcium.

Detailed information regarding the uses, composition, dosage, side effects and reviews of Digoxin tablets is detailed below.

Uses of the Digoxin tablet

Digoxin in tablets is used in the treatment, control, prevention and improvement of the following diseases, conditions and symptoms:

  • Treatment of heart failure in adults.
  • Treatment of atrial fibrillation in adults.

Mechanism of action and Pharmacology

Digoxin in tablets improves the patient’s condition in treatment by increasing the availability of intracellular calcium.


You should take into account that prior to the use of Digoxin tablets, ask your doctor for your professional opinion regarding the drug and what would be their recommendations for use, depending on their conditions or personal conditions at the medical or health level.

Similarly, ask how you can avoid possible side effects, caused by some type of reaction to the medication, pay attention to their indications or go to the laboratory where the medication is produced for more information, each dose will depend on a single condition therefore not must self medicate

The key aspects for a professional advice would be:

  • Altered response in thyroid disorders and hypermetabolic states.
  • Check and record your heart rate and blood pressure daily.
  • Reduction of efficacy in patients with hypocalcemia.
  • Risk of decreased cardiac output in patients with preserved left ventricular systolic function.
  • Risk of Digoxin toxicity as shown by cardiac arrhythmias , anorexia, nausea, vomiting, visual changes.
  • Risk of ischemia in patients with acute myocardial infarction.
  • Risk of severe sinus bradycardia or sinoatrial block.
  • Risk of vasoconstriction in patients with myocarditis .
  • Risk of ventricular arrhythmias during electrical cardioversion.
  • Risk of ventricular fibrillation in patients with Wolff-Parkinson-White syndrome .

Symptoms of Digoxin toxicity in babies include weight loss, growth retardation, abdominal pain and behavioral disturbances.

Each time you take more than one medication or mix it with certain foods or beverages, you will be at risk of an interaction with other medications.

Take Digoxin as recommended by your doctor. Do not consume quantities greater than those recommended. It is recommended to take this medicine at the same time every day. Monitoring of heart rate and blood pressure is necessary.

Consult your doctor if you experience any undesirable effects. Do not stop taking the medication without consulting your doctor.

Interaction with alcohol

The interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.


It is advisable to consult your doctor before consumption.

Interaction with Medicines such as:

  • Clarithromycin.
  • Pantoprazole.
  • Atorvastatin.
  • Gluconate of calcium.

Other interactions:

  • Disease.
  • Autrioventricular block.

This medication is not recommended in patients with AV block. Tell your doctor if you have heart disease. An alternative medication based on the clinical condition should be considered.

Hipopatasemia / Hipomagnesemia.

There is an increased risk of Digoxin toxicity in patients with low levels of potassium and magnesium. The baseline electrolyte should be obtained before starting the treatment. Close supervision is required.

This is not an exhaustive list of interactions. Always inform your doctor in advance about your medical history and current medications.

Contraindications of Digoxin in tablets

Hypersensitivity to Digoxin tablets is a contraindication. In addition, Digoxin tablets should not be used in patients with ventricular fibrillation .