Cisapride: Dosage, Precautions, Action Time, Side Effects and Interactions

It is a medicine used to help with the symptoms of certain types of stomach problems, such as heartburn.

Cisapride accelerates the stomach emptying and food movement through the stomach and intestine.

You may hear Cisaprida called by its brand name, Propulsid.

Presentation of Cisaprida

  • Cisapride is available as a tablet.

You should inform your doctor if your child is allergic to Cisapride.


For adults

Dismotilidad gastrointestinal
  • 5-10 mg PO q6hr at least 15 minutes PC and HS.

It may be necessary to increase to 20 mg in some patients.

For children

Dismotilidad gastrointestinal
  • 0.15-0.3 mg / kg / dosis PO q6-8hr; no debe exceder 10 mg / dosis.

Precautions in the administration

Talk to your doctor or pharmacist if your child has any of the following conditions:

  • Heart problems, especially heart rhythm problems.
  • Ulcers or bleeding from the stomach.
  • Blockage in the intestine.
  • Low potassium or calcium, or magnesium.
  • Kidney disease
  • Lung disease.

How should you give Cisaprida to your child?

Follow these instructions when you give Cisaprida to your child:


  • Administer the product exactly as directed by your doctor or pharmacist.
  • Give Cisaprida to your child at the same time every day.
  • Choose times that are easy for you to avoid losing doses.
  • Administer the medication between 15 and 30 minutes before meals and when lying down with a full glass of water.
  • Your child should not eat grapefruit or drink grapefruit juice while taking Cisapride.
  • You can crush the tablet or open the capsules and mix the contents with a glass of water or juice, as long as your child drinks all the liquid immediately after mixing it.

What should you do if your child misses a dose of Cisapride?

Administer the missed dose as soon as you remember it.

If it is almost time for the next dose, do not administer it after that time. Follow the next dose at the set time.

Action time

It may take several weeks for your child to feel the full benefit of this medication.

What are the possible side effects of Cisapride?

Check with your child’s doctor if your child continues to have any of these side effects and they do not go away:

  • Headache, lightheadedness, dizziness, or drowsiness.
  • Stomach ache.
  • Watery stools (diarrhea) or difficulty defecating ( constipation ).
  • Dry mouth.

Most of the following side effects are not common, but they can signify a serious problem. Call your child’s doctor right away or take your child to the emergency if you have any of these side effects:

  • Unexplained vomiting
  • Blurred vision or other vision changes.
  • Convulsions
  • Rapid or accelerated heartbeat.
  • Strong, irregular, or uneven heartbeats.
  • Swelling of the face, hands, legs, and feet.
  • Unusual weight gain

What safety measures should you take when your child is using the medication?

Do not give grapefruit or grapefruit juice to your child while you are taking Cisapride. There is a risk of serious heart rhythm problems if Cisapride and grapefruit are taken.


If more than one medication is necessary, the dose of Cisapride or the other medicines should be adjusted.

It is important to tell your doctor and pharmacist if your child takes any other medication (prescription, over-the-counter or herbal), which includes:

What other important information should you know about Cisapride?

Your child will require an ECG and other tests before and during the use of Cisapride. These tests minimize the risk of heart rhythm problems while taking Cisapride.

Be sure to keep all appointments in the clinic or doctor’s office.

Make a list of all medications your child takes to report to your doctor.

Do not share your child’s medications with others, and do not give your child someone else’s medication.

It is essential to keep Cisapride at room temperature, away from moisture, and in a cool place. It should not be exposed to sunlight.

The Cisaprida must be out of sight and reach of your child. It must be stored in a safe place.

Eliminate when the medication is outdated or expired.