Chlorpheniramine: Uses, Dosage, Forms of Medication, Interactions, Side Effects and Precautions

It is a synthetic drug used to counteract the histamine reaction, as in allergies.

It is administered orally or by intravenous, intramuscular or subcutaneous injection in the form of chlorpheniramine maleate.

Generic name: Chlorpheniramine maleate.

Uses of chlorpheniramine

Chlorphenamine is used in the treatment of:

The symptoms of allergic conditions, such as watery eyes, runny nose, sinusitis , rhinitis, hay fever and sneezing.

It is also used in the treatment of acute urticaria and angioedema (a condition similar to urticaria, but in which tissue swelling occurs under the skin).

Dosage of chlorpheniramine

The dose of chlorphenamine that the doctor recommends will be based on the following

  • The condition that is being treated.
  • Other medical conditions you have.
  • Other medications you are taking.
  • How you respond to this medication
  • The weight.
  • The height.
  • Age.
  • The gender.

The typical dose for adults for symptomatic relief is 4 mg three to four times a day.

For children

Six to 12 months: 1 mg twice a day.
From one to five years: 1-2 mg three times a day.
From six to 12 years: 2-4 mg three times a day.

It is important that you take chlorpheniramine exactly as prescribed by your doctor.

When should chlorpheniramine be avoided?

If you suffer from the following conditions:

  • Allergy to antihistamines.
  • Severe liver disease.

Forms of medication

Chlorphenamine is available in the following forms:

  • Disintegration tablet.
  • Extended-release capsule.
  • Extended launch suspension.
  • Extended release tablet.
  • Injectable solution.
  • Oral capsule
  • Oral solution.
  • Oral suspension.
  • Tablet oral.
  • Topical lotion

What interactions with other medications might you experience?

Almost all medications can have interactions, they modify or cancel the action of medications.

To avoid adverse drug interactions, always tell your doctor what prescription and non-prescription medications, vitamins, nutritional supplements and herbal products you are taking or plan to take.

Side effects of chlorpheniramine

Side effects may include:

  • Dizziness, drowsiness and / or blurred vision.
  • Greater sensitivity to the sun
  • Constipation .
  • Dry mouth, nose or throat.
  • Decreased coordination

What are the symptoms of overdose?

Call a doctor or ambulance immediately if you suspect an overdose and observe the following symptoms:

  • Fever.
  • Hallucinations
  • Weakness.
  • Shake.
  • Loss of consciousness.
  • Convulsions

When to stop using chlorpheniramine?

Stop using chlorpheniramine and call your doctor at once if you have a serious or strange side effect such as:

  • Rapid or uneven heart rate.
  • Humor changes.
  • Tremor, convulsion (convulsions).
  • Bruising or easy bleeding, unusual weakness.
  • Feeling short of breath
  • Urinating less than normal or nothing at all.

Precautions to be taken into account

Chlorpheniramine should be used with caution if you suffer from the following conditions:

  • Asthma .
  • Lung problems.
  • Heart problems.
  • High blood pressure ( hypertension ).
  • Glaucoma (an eye disorder that causes damage to the optic nerve).
  • Blockages in the stomach, intestines or bladder.
  • An enlarged prostate.
  • Epilepsy .
  • An overactive thyroid ( hyperthyroidism ).
  • Decreased liver function.
  • Difficulty urinating.
  • Diabetes.
  • Renal and hepatic insufficiency.
Other precautions

Avoid use in children under two years.

Use with caution in children under six years of age (this is related to the use of injections, tablets and syrup formats).

The elderly should receive lower doses.

This medication must be discontinued at least 48 hours before a skin test is performed, as it can cause unreliable results.

Chlorpheniramine is only recommended for use during pregnancy and lactation if the benefit outweighs the risk, so consult your doctor or pharmacist.

Tell your doctor or dentist if you are taking this medicine before surgery.

Postpone your alcohol intake while taking this medication as the effects of alcohol may increase.

Do not use this medicine if you have uncontrolled or untreated illnesses, such as glaucoma, asthma or COPD, heart disease, or a thyroid disorder.


Ask your doctor or pharmacist if it is safe for you to take chlorpheniramine if you have:

  • A blockage in your digestive tract (stomach or intestines) a colostomy or ileostomy.
  • Liver or kidney disease.
  • Cough with mucus or cough caused by smoking, emphysema or chronic bronchitis.
  • Enlarged prostate or urination problems.
  • Si toma potasio: Cytra, Epichlor, K-Lyte, K-Phos, Kaon, Chlor-Con, Polycitra, Urocit-K).