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It belongs to a group of drugs called statins, which regulate lipids.
Zarator tablets are used to treat primary hypercholesterolemia to lower high levels of cholesterol and other fats (triglycerides) in the blood and reduce the risk of coronary heart disease (CHD), including heart attack and angina , which can be caused by cholesterol. high .
There are usually no symptoms of high cholesterol, which can be due to a lifestyle (high-fat diet and lack of exercise) or it can be inherited (familial hypercholesterolemia).
Zarator tablets are used in the absence of symptoms in conjunction with a low-fat diet, if diet alone is not sufficient to lower cholesterol levels.
Zarator is also used to prevent the progression of coronary heart disease, if symptoms are already present; also to treat people with diabetes or a history of stroke, to reduce the need for surgery, and to reduce the risk of stroke or peripheral vascular disease.
What is the Zarator’s mechanism of action?
Zarator tablets contain atorvastatin which belongs to a group of cholesterol-lowering medicines called statins.
The body needs cholesterol for many functions, such as building cell membranes, producing certain hormones, and transporting fat-soluble vitamins throughout the body.
However, if there is more cholesterol than the body needs, it deposits on the walls of the arteries where it can build up, blocking the arteries and causing hardened areas called plaque, increasing the risk of heart disease.
The atorvastatin in Zarator reduces the production of cholesterol in the liver by inhibiting HMG-CoA reductase, an important enzyme involved in the synthesis of cholesterol.
Cholesterol is released into the blood as low-density lipoprotein (LDL-C) to distribute cholesterol throughout the body; High-density lipoprotein (HDL-C) collects excess cholesterol from the arteries and returns it to the liver for disposal or reuse.
The Atorvastatin in Zarator lowers the levels of LDL-C, which is known as “bad” cholesterol, as it can cause blocked arteries, and it also increases the levels of HDL-C, which is known as the “good” cholesterol (HDL ) which helps unblock hardened arteries.
What are the components of the Zarator?
Zarator contains the active ingredient atorvastatin, which is a cholesterol-lowering drug that belongs to the group of drugs called statins.
Also contains calcium carbonate, cellulose – microcrystalline, lactose, croscarmellose sodium, polysorbate 10, hydroxypropyl cellulose, magnesium stearate, white opadry YS-1-7040, simethicone emulsion.
Treatment of high cholesterol (hypercholesterolemia) with Zarator
Zarator tablets are used to treat high cholesterol (hypercholesterolemia), which can increase the risk of heart disease.
The body needs cholesterol for many functions, such as building cell membranes, producing certain hormones, and transporting fat-soluble vitamins throughout the body.
However, if there is more cholesterol than the body needs, it deposits on the walls of the arteries where it can build up, blocking the arteries and causing hardened areas called plaque, increasing the risk of heart disease.
Zarator is used to reduce high levels of cholesterol and other fats (triglycerides) in the blood, by reducing the production of cholesterol in the liver, where it inhibits HMG-CoA reductase, an important enzyme involved in the synthesis of cholesterol.
Lowering cholesterol with Zarator
Zarator tablets contain the cholesterol-lowering statin medication atorvastatin, which is used to lower the levels of cholesterol and other fats (triglycerides) in the blood to reduce the health risks associated with coronary heart disease (CHD).
Some health risks related to coronary heart disease are heart attack and angina that can be caused by high cholesterol.Atorvastatin in Zarator reduces the production of cholesterol in the liver by inhibiting HMG-CoA reductase, an important enzyme involved in the synthesis of cholesterol.
Zarator lowers levels of “bad” cholesterol (LDL) that can cause arteries to harden and block, and it also increases levels of “good” cholesterol (HDL) which helps unblock hardened arteries.
There are usually no symptoms when you have high cholesterol, which can be due to a lifestyle (high-fat diet and lack of exercise) or it can be inherited.
Effects of alcohol and grapefruit on Zarator
Alcohol if drunk in large amounts can increase the risk of liver problems when taking Zarator. Grapefruit juice in large amounts (more than a liter a day) can also increase the risk of side effects, as it increases the amount of Zarator that gets into your blood.
What are the side effects of Zarator?
The most common side effects when taking Zarator tablets include:
- Constipation.
- Diarrhea.
- Abdominal pain.
- Sickness.
- Headache.
- Dizziness
- Infections such as nasopharyngitis (the common cold).
- Urinary tract infection.
- Muscle pain.
- Tenderness or weakness, not caused by exercise.
- Pain in swollen joints.
- Epistaxis (nosebleeds).
- Hyperglycemia (high blood sugar).
What are the contraindications of the Zarator?
You should not use Zarator tablets if:
- Are allergic to atorvastatin or any ingredient in Zarator.
- You have active liver disease.
- Are pregnant, planning to become pregnant, or are breastfeeding.
Also if you are taking other medicines that interact with Zarator, including:
- Macrolide antibiotics: such as clarithromycin, erythromycin, fusidic acid, ritonavir for itraconazole and use of ketoconazole to treat fungal infection, cyclosporine, used to suppress the immune system, digoxin for heart failure, antacids for indigestion.
- Anticoagulants such as coumarin.
- Medicines such as verapamil or diltiazem for high blood pressure, angina, or other heart conditions.
- Amiodarone for irregular heartbeat.
- Some contraceptives.
What medications interact with Zarator?
Several medications interact with Zarator tablets and should not be taken while taking Zarator or only after discussion and instructions from your doctor:
Drugs that cause a serious reaction or increase the risk of side effects with Zarator: macrolide antibiotics, such as clarithromycin, erythromycin, fusidic acid, HIV protease inhibitors, such as ritonavir, itraconazole, and ketoconazole to treat fungal infection.
Drugs that affect Zarator:
- Other cholesterol-lowering medications such as gemfibrozil, cyclosporine, used to suppress the immune system.
- Medicines such as verapamil or diltiazem, for high blood pressure, angina, or other heart conditions.
- Amiodarone for irregular heartbeat.
- Blood thinners such as warfarin, antacids for indigestion.
Drugs that are affected by Zarator: digoxin for heart failure; Oral contactees.
How should the Zarator be taken?
You should take your Zarator tablets with a glass of water once a day, preferably in the evening after dinner, although you can take Zarator with or without food.
Zarator is most effective at night when your body is resting and your liver produces the most cholesterol. The dose you take depends on how well you respond to lowering cholesterol.
You should continue taking Zarator tablets for the time recommended by your doctor, which may be for the rest of your life as Zarator helps keep your cholesterol levels too high and if you stop taking Zarator, your cholesterol levels may rise again. .
How long should I take Zarator?
You should continue taking Zarator tablets for the time recommended by your doctor, which may be for the rest of your life as Zarator helps keep your cholesterol levels too high and if you stop taking Zarator, your cholesterol levels may rise again. .
Missed dose of Zarator
If you miss a dose of Zarator, take it as soon as you remember, unless it is time for the next dose, then skip the missed dose. Do not take a double dose
How should the Zarator be stored?
You should store your Zarator below 25 ° C in a cool, dry place.