Vivera: Uses, Administration, Mechanism of Action, Side Effects and Risks

Quickly relieves gastrointestinal disorders by accelerating the natural healing process.

Vivera medication is formulated with B.Aliv®, a widely studied probiotic that naturally balances the intestinal microflora.

It was formulated by Merck with B.Aliv®, one of the most researched and most effective probiotics in the world for treating gastrointestinal disorders, which regenerates intestinal flora.

As a food supplement, Vivera medicine comes in a practical and innovative ready-to-use powder sachet, making it ideal for children and adults to use anywhere while traveling.

It is a truly winning proposition for children and adults, especially when looking for natural and effective options.

What are probiotics?

Probiotics are live bacteria and yeasts that are good for you, especially your digestive system. We usually think of these germs that cause disease. But your body is full of bacteria, good and bad.

Probiotics are often called “good” or “helpful” bacteria because they help keep your gut healthy.


You can find probiotics in supplements and some foods, like yogurt. Doctors often suggest helping with digestive problems.

The probiotics in the drug Vivera are increasingly being used as a treatment for various medical conditions, including allergic diseases (atopic dermatitis and possibly allergic rhinitis ), bacterial vaginosis, urinary tract infections, and prevention of tooth decay or respiratory infections.

The probiotics in the drug Vivera are used to treat a variety of gastrointestinal (GI) disorders.

What are the health benefits of probiotics?

Probiotics may seem new to the food and supplement industry, but they have been with us since our very first breath.

During a birth through the birth canal, a newborn picks up Bacteroides, Bifidobacterium, Lactobacillus, and Escherichia coli bacteria from its mother.

These good bacteria are not passed on when a cesarean is performed and are why some babies born by cesarean section have allergies, less-than-optimal immune systems, and lower levels of intestinal microflora.

They are believed to protect us in two ways. The first is the role they play in our digestive tract.

We know that our digestive tract needs a healthy balance between good and bad bacteria, so what hinders this? It seems that our lifestyle is both the problem and the solution.

Poor food selection, emotional stress, lack of sleep, overuse of antibiotics and other drugs, and environmental influences can shift the balance in favor of harmful bacteria.

When the digestive tract is healthy, it filters and removes things that can harm it, such as harmful bacteria, toxins, chemicals, and other waste products.

The healthy balance of bacteria helps regulate gastrointestinal motility and maintain intestinal barrier function.

Research has shown some benefits for the use of probiotics for infectious diarrhea, antibiotic-associated diarrhea, intestinal transit, abdominal pain and bloating, ulcerative colitis, Helicobacter pylori infection, non-alcoholic fatty liver disease (NAFLD) in English) and necrotizing enterocolitis.

The other way that probiotics help is their impact on our immune systems. Some believe that this role is the most important. Our immune system is our protection against germs.

When it doesn’t work properly, we can suffer from allergic reactions, autoimmune disorders (for example, ulcerative colitis, Crohn’s disease, and rheumatoid arthritis), and infections (infectious diarrhea, H. pylori, skin infections, and vaginal infections).

By maintaining the correct balance from birth, the hope would be to prevent these ailments. Our immune system can benefit any time balance is restored, so it is never too late.

Research on the benefits of probiotics has diversified, and new areas are emerging.

Preliminary research has linked them to supporting the health of the reproductive tract, oral cavity, lungs, skin, and intestinal and brain axis, and the prevention and treatment of obesity and type 1 and type 2 diabetes.

What does the medicine Vivera do?

Some common conditions it treats are:

  • Irritable bowel syndrome.
  • Inflammatory bowel disease (IBD).
  • Infectious diarrhea (caused by viruses, bacteria, or parasites).
  • Antibiotics cause diarrhea.

There is also some research showing that they are helpful for problems in other parts of your body. For example, some people say they have helped with:

  • Skin conditions, such as eczema.
  • Urinary and vaginal health.
  • Prevention of allergies and colds.
  • Oral health.

How should people take probiotics?

The requirements for a microbe to be considered a probiotic are that the microbe must be alive when administered, must be documented to have a health benefit, and must be administered at levels to confer a health benefit.

A frequently cited rule of thumb is to take at least 1 billion colony-forming units (CFUs) daily.

These live microorganisms won’t deliver the promised benefits if they don’t stay alive.

The manufacturer and the consumer should pay close attention to the storage conditions under which the particular microorganism will survive and at the end of its shelf life.

Potency will indicate the number of viable bacteria per dose, and purity has to do with the presence of contaminating or ineffective bacteria.

The other thing to remember is that these microorganisms are not all created equally. The genus, strain, and species must be the same for the results found in the study as the results one expects to get from taking it.

For example, with the Lactobacillus rhamnosus GG strain, the genus is Lactobacillus, the species is rhamnosus, and the strain is GG. If any of those are different in your supplement, you may not get the same results.

With the growing popularity of Rivera, there are a wide variety of other supplements that you can choose from. The most important thing is to determine what type of probiotic microorganism you need for your condition.

Don’t just take the supplement that most agencies provide. You need to do your research and make sure there are scientific studies to back up what you take.

New research is emerging, so keep looking if you can’t find what you need right now. A doctor can help you decide if trying Rivera might be helpful for you and can advise you on the amount that may be appropriate for you.

Mechanism of action

The gastrointestinal tract plays a vital role as an interface between the host and the environment. It is colonized by about 10 billion microbes of many different species, weighing 1–2 kg.

Only a minority (300–500) of these species can be grown in vitro and studied.

Intestinal epithelial cells can distinguish pathogenic from nonpathogenic bacteria based on their invasiveness and the presence of flagella. However, the exact mechanisms that allow them to do this have not been fully elucidated.

The precise mechanism (s) of action of Vivera or probiotics has not been clarified so far. Possible tools to consider include:

  • Modulating gastrointestinal immunity by altering inflammatory cytokine profiles and downregulating pro-inflammatory cascades or inducing regulatory mechanisms in a strain-specific manner.
  • The displacement of gas-producing bacterial species deconjust bile salts and, therefore, inhibits pathogenic bacterial adherence.
  • Alteration of the bacterial flora by acidifying the colon by fermentation of nutrients.
  • Improved epithelial barrier function.
  • Induction of opioid and cannabinoid receptors in intestinal epithelial cells.
  • Reduction of visceral hypersensitivity, spinal afferent traffic, and stress response.

What types of probiotics does the drug Vivera contain?

Probiotic products from foods, beverages, and supplements contain bacteria and yeast.

Until the 1960s, the only intestinal microflora they could identify were clostridia, lactobacilli, enterococci, and E. coli. Since then, innovative techniques have discovered many more bacteria.

There are several different types of probiotics, and their health benefits are determined by the work they do in the gut. They must be identified by their genus, species, and strain level. The Vivera drug is of the Lactobacillus rhamnosus GG or LGG type.


There are more than 50 species of lactobacilli. They are found naturally in the digestive, urinary, and genital systems.

Foods fermented, such as yogurt and dietary supplements, contain these bacteria. Lactobacillus has been used to treat and prevent various diseases and conditions.

Some of the lactobacilli found in food and supplements are:

Lactobacillus acidophilus, L. acidophilus DDS-1, Lactobacillus bulgaricus, Lactobacillus rhamnosus, Honeymoon Gazette, Nature’s Animal Parts, Lactobacillus, Nature’s Playgrounds, and Lactobacillus.

Studies have shown some benefits related to Lactobacillus and the treatment and prevention of:

  • Yeast infections, bacterial vaginosis, urinary tract infection, irritable bowel syndrome, antibiotic-related diarrhea, traveler’s diarrhea, and diarrhea caused by Clostridium difficile.
  • Treatment of lactose intolerance, skin disorders (fever blisters, eczemaacne, and mouth ulcers), and prevention of respiratory infections.

When can Vivera help?

As the probiotics in the drug Vivera have become more popular, researchers continue to study these “good” bacteria.

The results show that they can help with digestive problems and other health problems ranging from eczema to childhood colds.

These natural microbes can be found in foods like yogurt and in supplements that come in pills, capsules, powders, and liquids. Choosing Vivera as a supplement is essential. They have different strains of bacteria, and each one is believed to have other effects on your health.

In 2008, a panel of experts at Yale University reviewed the research and ranked various strains of probiotics based on their effectiveness against specific health problems.

They added to their findings in 2012. Here are some of the conditions that got the best ratings for probiotic treatment.

Infant diarrhea

The researchers found that Vivera can reduce bouts of diarrhea in children. But it doesn’t seem to work that well to prevent it. For infant diarrhea, Lactobacillus GG in Vivera may be helpful.

Bifidobacterium bifidum combined with Streptococcus thermophilus can help keep children safe from diarrhea caused by rotavirus.

Diarrhea from antibiotics

Sometimes taking Vivera can cause diarrhea. These potent drugs can kill the “good” bacteria while attacking the bad. The probiotics in the medicine Vivera can help prevent this type of diarrhea in both adults and children.

Inflammatory bowel disease (pouchitis and ulcerative colitis)

If you have surgery for ulcerative colitis, the surgeon will sometimes create a pouch after most of your colon is removed. Sometimes your lining can become irritated and inflamed. This is called pouchitis.

Studies show that Vivera can help prevent this, but the probiotics in the drug Vivera are not as helpful in treating them once they start.

Probiotics can help prevent flare-ups of ulcerative colitis. But researchers don’t think they can do much to treat an attack.


If your child has an allergic skin reaction to cow’s milk, Vivera can help. Try Vivera for atopic eczema. If eczema runs in your family, taking the probiotics in the drug Vivera during pregnancy can prevent your newborn from getting it.

Irritable bowel syndrome

People with irritable bowel syndrome may have diarrhea, constipation, or both. One sachet of Vivera can help regulate bowel movements and ease bloating.

Enterocolitis necrotizante

Premature babies are at risk for this severe disease. The tissue in the intestines begins to die. The intestines become inflamed, and a hole can form.

Recent studies show that using Lactobacillus rhamnosus GG with bovine lactoferrin supplement can help keep it under control. Bifidobacterium infantis combined with Lactobacillus acidophilus can also help prevent this problem in sick newborns.

Other possible uses of the drug Vivera

Researchers have found other ways that these good bacteria can keep people healthy. Vivera probiotics can also help these conditions:

  • Infant colds.
  • Urinary tract and vaginal health.
  • Allergies and asthma.
  • Lactose intolerance.
  • Childhood stomach and lung infections.
  • Oral health.
  • Joint stiffness
  • Traveler’s diarrhea.

How to use Vivera safely

Humans have consumed probiotics in one form or another for over 100 years, with an overall good safety record.

The Food and Drug Administration regulates probiotics like food, not medicine. Unlike pharmaceutical companies, probiotic supplement manufacturers do not have to prove that their products are safe or work.


However, questions and concerns have been raised about the safety of the Vivera administration in the context of serious illness.

Probiotic sepsis is the most feared complication related to the administration of probiotics. Lactobacillus is a rare but documented cause of endocarditis in adults.

There are several reports in the literature of bacteremia in adults and children in probiotic administration.

Other safety concerns relate to the unpredictability of immune modulation through the change in intestinal flora in certain disease states.

For example, it is worsening of Crohn’s disease (CD) in patients taking some probiotic formulations or exacerbation of indomethacin-induced enteropathy in animal models with Lactobacillus GG.

As rare as these complications appear to be, the safety profile of probiotics must be specifically studied, especially in hospitalized patients.

No formal clinical trials evaluate the safety of probiotics, as there is safety data on regulated drugs. At this time, we can only rely on case reports, which are undoubtedly suboptimal.

What are the side effects and risks of probiotics like Vivera?

Supplements play an essential role when the diet is insufficient to meet our needs.

In the case of probiotics, Rivera and diet are the ideal sources of probiotics. These are live bacteria and must be carefully monitored, stored, and combined to obtain the health benefits for which one would be taking them.

At this time, supplements like Rivera are not monitored in the US in terms of food or drugs. They are covered by the Dietary Supplements Health and Education Act of 1994 (DSHEA).

This requires that the manufacturer of Rivera, dietary supplements, or dietary ingredients be responsible for ensuring that a dietary supplement or ingredient is safe before it is placed on the market.

The only time the United States Food and Drug Administration (FDA) can participate is if it is necessary to take action against a manufacturer of Rivera after marketing the supplement and then discovering that it is unsafe.

This means that as much as we know about Rivera, we cannot be sure of the safety or content of the supplement for us.

There is a Voluntary Certification Program by which a manufacturer of this type of supplement can choose to be evaluated. (CL) is the leading provider of independent test results and information to help consumers and healthcare professionals identify the best quality health and nutrition products.

Products that have passed their tests for identity, strength, purity, and disintegration can imprint the Seal of Approval on their product. This is a step to ensure you get the amount and probiotic promised by the manufacturer.

All people who decide to take this supplement should take precautions, but this is especially true for children, pregnant women, the elderly, and people with compromised immune systems.

For people with compromised immune systems due to illness or treatment for a disease (such as chemotherapy for cancer), taking vera can increase the chances of getting sick.

The use of various probiotics such as Rivera for immunocompromised patients or patients with a leaky gut has led to infections and sepsis (infection of the bloodstream).

Recently a case of bacteremia (bacteria in the bloodstream) was found when Lactobacillus GG was administered Lactobacillus GG to a person with severe inflammatory bowel diseases and mucosal alteration. Always speak with a doctor before taking Vivara in these circumstances.


The drug Vivera is a therapeutic class that is increasingly used for various gastrointestinal disorders. It appears to alter the intestinal microflora and can exert its effect (s) by multiple mechanisms.

There are many species of probiotics, and it is generally accepted that not all probiotics are created equal. Efficacy can be due to a single strain or multiple strains, or a combination of different probiotics.

The drug Vivera decreases the duration of symptoms in acute infectious diarrhea. Probiotics are as effective as standard therapy (mesalamine) in inducing or maintaining remission in ulcerative colitis or Crohn’s disease .

When added to standard therapy, Vivera does not provide additional benefits compared to standard treatment alone.

Vivera is safe in immunocompetent hosts in an outpatient setting.

However, administration of Vivera to immunocompromised, chronically ill, hospitalized patients with gastrointestinal disorders and indwelling catheters may predispose them to probiotic sepsis.

Specifically, in gastrointestinal disorders where intestinal permeability and intestinal immunity can be compromised, adding Vivera can increase the translocation of bacteria in the bloodstream.

Until further studies on the safety of probiotics in hospitalized patients, we caution against their use in this context.

Future studies should address many of the remaining questions related to basic knowledge of probiotics, such as the composition of the human intestinal flora, fecal viability and recovery rates, and physiological and immunological effects.