Index
It is a semi-synthetic derivative of colchicine, a natural anti-inflammatory glycoside that originates from the flower seeds of the glorious superba.
Tiocolchicoside is a drug used for the adjunctive treatment of painful muscle contractures in acute spinal pathology in adults and adolescents from 16 years of age.
It is anti-inflammatory and analgesic. It works as a competitive GABAA receptor antagonist.
Indications
This medicine provides relief for:
- Rigidity in diseases of the spine.
- Muscle contractions
- Joint diseases.
- Nervous diseases.
- Rheumatoid arthritis .
- Ankylosing spondylitis.
- Rheumatism.
- Fever
- Headache
- Painful muscle spasm
Mechanism of action
Tiocolchicoside inhibits the action of cyclooxygenase in the body and, consequently, reduces pain and swelling.
General warnings
If you use other medicines:
Report the use of all your current medications, including herbs and supplements, to your doctor to avoid the chances of a possible interaction with Tiocolchicoside.
Kidney disease:
This medicine should be used with caution in patients with kidney disease or impaired normal kidney function due to the increased risk of serious side effects.
Close monitoring of renal function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary depending on the clinical status of the patient.
Driving machinery:
The use of this medicine can cause symptoms such as drowsiness, impaired judgment, impaired body movements, etc., in some patients.
Therefore, it is recommended that you do not engage in any activities that require high mental alertness, such as driving a vehicle or operating heavy machinery, during treatment with this drug.
Use in children:
The use of this medicine is not recommended in children and adolescents under 16 years of age.
Use in women of childbearing age:
Women of childbearing potential should adopt adequate contraception to avoid pregnancy during treatment with this medicine.
Impaired fertility:
The use of this medicine can cause impaired fertility in men. Discuss all the risks and benefits with your doctor before taking this medicine.
Other warnings
People with a history of seizures should avoid taking Tiocolchicoside as it has seizure activity.
Before using this medication, tell your doctor if you: have gastrointestinal disorders, are allergic to any ingredient in Tiocolchicoside, have other allergies, are already taking any medications, are an alcoholic, are recovering from surgery, are pregnant, or are breastfeeding. To a baby.
Dosage
Dosage is determined by your doctor based on your condition. However, the usual dose in adults is approximately 16 mg per day orally or 8 mg intramuscularly per day.
Missed dose
Contact your doctor or pharmacist for further instructions if you miss a scheduled dose of this medication. Do not take extra medications to make up for the missed dose.
Overdose
Contact your doctor immediately if an overdose of this drug is suspected.
Side effects
In addition to its desired effect, Tiocolchicoside can cause some unwanted effects as well. In such cases, you should seek medical attention immediately. This is not an exhaustive list of side effects and it can vary from person to person.
Inform your doctor if you experience any adverse drug reaction.
Side effects of Tiocolchicoside.
- Itching and rash.
- Swelling of the face, lips, eyelids, tongue, hands and feet.
- Fainting and drowsiness.
- Nausea and vomiting
- Yellowing of the skin and eyes.
- Dry mouth.
- Headache.
Other side effects that you may experience when using this drug include the following:
- Dizziness
- Fatigue.
- Allergic reaction.
- Abdominal pain.
- Diarrhea.
- Dyspepsia.
- Sensitivity to sunlight.
- Gases.
Contraindications
Tiocolchicoside is contraindicated in patients with a history of sensitivity to the components of the drug.
Interactions
All drugs interact differently from person to person. You should check all possible interactions with your doctor before starting any medication.
Interaction with alcohol
Description: interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Disease interactions : not reported.
Interactions with food: not reported.
Laboratory interactions: not reported.
This is not an exhaustive list of possible Tiocolchicoside interactions. You should consult your doctor about all possible drug interactions you are taking.
Storage
Store in a cool place, out of the reach of children.
