Testoviron: Uses, Contraindications, Precautions, Interactions, Warnings, Dosage, Method of Use and Unwanted Effects

It is used to replace testosterone in adult men.

This injection is for treating various health problems due to testosterone deficiency ( male hypogonadism ).

This condition should be confirmed with two separate testosterone blood measurements and should include clinical symptoms such as:

  • Impotence.
  • Sterility.
  • Poor sexual desire.
  • Fatigue.
  • Depressed mood
  • Loss of bone due to low levels of hormones.

Contraindications

  • If you have hypercalcemia (excess calcium in the blood) secondary to malignant tumors.
  • If you have or have ever had a liver tumor.
  • If you have kidney disease.
  • If you have high blood pressure.
  • If you have severe liver dysfunction.

Usage precautions

Talk to your doctor or pharmacist before using Testoviron.

As a precaution, he periodically undergoes an andrology visit with a rectal examination of the prostate.

Before and during treatment, the doctor should perform the following blood tests: testosterone levels in the blood and complete blood count.

If you are predisposed to edema (swelling), your doctor should monitor you carefully, as androgen treatment can increase sodium retention and, consequently, fluid.

 

Benign and malignant liver tumors that can cause life-threatening intra-abdominal bleeding have been observed after using Testoviron.

If you experience disturbances in the upper abdomen, consult your doctor, who will monitor you to rule out the presence of a liver tumor.

If you have severe heart, liver, or kidney disease, treatment with Testoviron can cause severe complications in the form of water accumulation in your body, sometimes accompanied by heart failure (congestive).

Tell your doctor if you have high blood pressure or are being treated for high blood pressure, as testosterone can increase your blood pressure.

Elderly patients treated with androgens may be at increased risk for prostate hyperplasia (enlarged prostate).

There is no precise data that androgens cause prostate cancer (prostate cancer); they may promote growth if it is already present. Therefore, before prescribing therapy with testosterone preparations, the doctor must rule out the presence of prostate carcinoma.

Testoviron can cause excessive sexual stimulation. If this happens, talk to your doctor.

If you are an older adult, your doctor will carefully observe that this medicine does not cause excessive and unwanted physical, nervous and mental stimulation.

Testoviron should only be injected intramuscularly and very slowly like all oily solutions.

Pulmonary microembolism of oil solutions (tiny oil droplets in the arteries of the lungs) can cause signs and symptoms such as:

  • To.
  • Difficulty breathing.
  • Chest pain.

Other signs and symptoms may also appear, such as:

  • General discomfort.
  • Sweating
  • Dizziness
  • Paresthesia (change in sensation, for example, tingling).
  • Fainting.

Treatment consists of supportive measures, such as the administration of oxygen.

If you suffer from sleep apnea (episodes of stopping your breathing while sleeping), this can be accentuated with the use of Testoviron.

This drug is not indicated to increase muscle mass in healthy individuals or promote physical performance.

Testoviron should not be used in women. It can cause jaundice (yellowing of the skin and the whites of the eyes) and signs of masculinization, such as acne and abnormal hair growth in typical body areas. Man) and voice alteration.

For those who play sports

The use of the drug without therapeutic need constitutes doping and, however, can determine positivity to doping tests.

Children and adolescents

The use of Testoviron is contraindicated in children and adolescents. In boys, testosterone, in addition to having masculinizing effects, can affect bone maturation, resulting in decreased growth in height.

Patients with liver failure

The use of Testoviron is contraindicated in patients who have or have had liver tumors.

Drug interactions

Tell your doctor if you are taking the following medications:

  • Phenobarbital (antiepileptic medicine) can reduce the effectiveness of Testoviron.
  • Coumarin derivatives (anticoagulants used to thin the blood) because the doctor will carefully monitor the coagulation parameters.

Testoviron can also modify the glucose tolerance test:

If you have diabetes, consult your doctor before taking Testoviron, as the dose of insulin or oral antidiabetic medications may need to be adjusted.

Warnings

Testosterone replacement therapy can reversibly reduce spermatogenesis (the production of sperm).

Driving and using machines

The drug Testoviron does not affect the ability to drive and use machines.

Dosage and method of use

  • Follow exactly the instructions for administering this medicine indicated by your doctor or pharmacist.
  • If you are not sure, talk to your doctor or pharmacist.
  • This medication is for intramuscular use only.
  • The oily solution must be injected very slowly.

The recommended dose is:

  • For androgen-dependent target organ development and stimulation and initial treatment of deficient symptoms: one 250 mg vial every 2-3 weeks.
  • To maintain an adequate androgenic effect: one 250 mg vial every 3 to 4 weeks.

Depending on individual needs, the doctor may decide to shorten the intervals between injections, while in many cases, longer intervals are sufficient, up to 6 weeks.

Before starting treatment, and occasionally at the end of an interval between injections, your doctor will measure testosterone levels in your blood.

Levels below average values ​​indicate the need to shorten the interval between injections, which should be extended for high levels.

Use in the elderly

No dose adjustment is required for elderly patients.

Overdose

In case of accidental ingestion or overdose of Testoviron, inform your doctor immediately or contact your nearest hospital. No specific therapeutic measures are necessary; the doctor will decide whether to stop the treatment or reduce the dose.

Unwanted effects

This medicine can have side effects like all medicines, although not everyone gets them.

The most common side effects of Testoviron are:

  • Pain at the injection site.
  • Erythema (redness) at the injection site.
  • Cough and dyspnea (shortness of breath) during or immediately after the injection.

Side effects with a standard frequency are :

  • We have increased red blood cell count.
  • Hematocrit (percentage of red blood cells) and hemoglobin (the oxygen-carrying component of red blood cells) are evidenced by regular blood tests.

Other side effects, for which the frequency cannot be estimated, are shown below:

  • Benign and malignant liver tumors.
  • Polycythemia (increase in the number of red blood cells in the blood).
  • Allergy.
  • Abnormal liver function tests
  • Jaundice (yellowing of the skin and the whites of the eyes).
  • Acne.
  • Alopecia (hair loss).
  • Acne.
  • Urticaria (itching and small spots on the skin).
  • Itch.
  • Different types of reaction at the injection site (pain, redness, induration, swelling, inflammation).
  • Increase in prostate-specific antigen (PSA).
  • Increase or decrease in sexual desire.
  • Gynecomastia

Injections of oil solutions such as Testoviron have been associated with widespread reactions:

  • Tos.
  • Difficulty breathing and chest pain.
  • General discomfort.
  • Sweating
  • Dizziness
  • Paresthesia (impaired sensation, for example tingling).
  • Fainting.

Administration of testosterone in high doses or for long-term treatment can cause:

  • Anxiety.
  • Hypercalcemia (increased amount of calcium in the blood).
  • Fluid retention (accumulation of fluid in the tissues).
  • Edema (swelling).

Your doctor will need to follow you carefully if you show a similar trend, especially if you have severe heart or kidney problems, have asthma, or suffer from epilepsy.

High doses of testosterone or its derivatives inhibit the secretion of gonadotropins (the hormones that stimulate the testes), resulting in testicular atrophy.

Long-term, high-dose treatment with Testoviron inhibits spermatogenesis (the maturation process of male germ cells, which ends with the formation of sperm).

Talk to your doctor if you experience frequent erections. Your doctor will decide whether to reduce the dose or stop treatment to avoid injury to the penis.

Unwanted Effects Report

Talk to your doctor or pharmacist if you experience any side effects, including those not listed in this article.

Expiration and conservation

Keep this medicine out of sight and reach of children.

Do not use this medicine after the expiration date stated on the carton after expiry. The expiration date refers to the last day of that month. The expiration date refers to the product in intact packaging, adequately stored.

Do not dispose of any medicine through sewage or household waste. Ask your pharmacist how to dispose of medications you no longer use. This will help protect the environment.

The appearance of Testoviron and contents of the package

Testoviron is a clear, yellowish oil solution. It is available in packets (box) containing 1 vial of 250 mg / 1 ml.