Spiramycin: Administration, Side Effects, Precaution and Storage

It is an antibiotic known as a macrolide antimicrobial agent, which is used to treat various infections, such as:

  • Group A beta-hemolytic streptococci.
  • Staphylococci.
  • Pneumococci.
  • Gonococos.
  • Toxoplasmas.

Administration of Spiramycin

The patient should read the instructions for use before starting the treatment to clarify any doubts that may arise and if the information provided is not enough, ask the pharmacist or your treating doctor.

Spiramycin should be ingested as recommended by the treating physician, it is not necessary to exceed the dose because this will not make the infection improve faster. If the drug causes stomach upset, it can be ingested with food.

The patient should avoid losing the doses recommended by his doctor and should take the antibiotic in the indicated time interval to ensure that the Spiramycin is constantly kept in the blood attacking the infection.

Although there are noticeable short-term improvements, the patient must finish the treatment to ensure the extermination of the infection, otherwise he runs the risk of it being reactivated but this time being immune to the medicine and therefore more difficult to cure.

Side effects

This drug may cause the following mild side effects, but if they persist for a long time, the patient should contact their treating physician:

  • Sickness.
  • Vomiting
  • Indigestion.
  • Upset stomach or diarrhea.

Spiramycin rarely generates allergic reactions, however some patients may present the following symptoms and if this is the case, they should contact their doctor immediately:

  • Itching or burning in the extremities of the body.
  • Swelling of the throat, tongue, or face.
  • Skin rash, like a kind of rash.
  • Redness on the cheekbones of the face.
  • Difficulty breathing fluently.
  • Constant dizziness

The patient should stop treatment with Spiramycin if the following severe symptoms occur:

  • Disorientation.
  • Difficulty locating in space and time.
  • Excessive sweating
  • Involuntary movements of the body.
  • Elevated body temperature
  • Frequent fainting
  • Difficulty breathing.
  • Abdominal pain.
  • Dizziness
  • Body weakness
  • Anxiety.
  • Vomiting


It is important that the patient notify their doctor before starting treatment with Spiramycin if they have suffered from:

  • Liver diseases
  • Drug allergies.
  • Respiratory infections.
  • Renal calculus.
  • High tension.

It is not known if its use during the gestation process of pregnancy is risky for the unborn, so it should be used only if it is strictly necessary and under medical supervision.

Women who are breastfeeding should consult their doctor if they can ingest this drug, because its components can pass into breast milk and be harmful to the health of the baby.

Long-term use of Spiramycin can lead to other infections, such as:

  • Gallbladder infections.
  • In the case of women, the appearance of vaginal yeast.
  • Throat and chest infection.

The patient who is in treatment should avoid the consumption of alcoholic beverages, because they can reduce the effectiveness of the drug, thus delaying the cure of their condition.

The treating physician must know all the medications that the patient is using, such as:

  • Cyclosporine.
  • Carbamazepine.
  • Theophylline
  • Warfarin .
  • Triazolam.
  • Terfenadina.
  • Felodipina.
  • Astemizole.
  • Cisaprida.

On some occasions this medicine could interfere with the effectiveness of contraceptive pills, so the patient must take other preventive measures to avoid an unwanted pregnancy.

Some medications when interacting with Spiramycin can decrease their effectiveness so the patient should tell his doctor everything he is taking to take preventive measures.

Storage of Spiramycin

This medicine should be stored in a place that is at room temperature. It cannot be in contact with moisture, heat and sunlight on a frequent basis. It is not necessary to keep it refrigerated.

It should be out of the reach of children and pets because its use without medical supervision can be harmful to health or have serious side effects.

If the patient suspects that a child or pet accidentally ingested several doses of this medicine, he should immediately contact a doctor to validate that there are no short- or medium-term dangers or damage to the health of the affected person.

If the medicine is out of date, the patient should consult his doctor whether or not he can use it until its supply is exhausted, or else it should be discarded immediately.