Polaramine: Administration, Presentations, Components, Interactions, Side Effects and Precautions

It is used to treat rashes, allergies, runny noses, watery eyes, sneezing, itching, hives, and other common cold symptoms.

Polaramine is an antihistamine that blocks the natural effects of histamine.

This medicine can also treat other symptomatologies other than those mentioned above.

Polaramine Administration

This medication must be taken exactly as directed by your doctor.

To make it easier to take, drink it with a glass of water; you can also take it with food accompaniment.

Take the tablets whole, do not chew, break or crush them, much less the presentations in their prolonged-release form, as they are specially made to be released slowly in your body.

The best way to take the correct dose is by measuring it with a special measuring cup for medicines; never measure it with a regular spoon.


You can ask your pharmacist where to get a measuring device if you do not have one.

Polaramine tablets:

  • Adults and children over 12 years: one polar amine tablet every 6 hours.
  • After obtaining initial relief, the dose can be reduced to 1 tablet as needed.

Do not give polar amine tablets to children under 12 years of age.

Syrup of polyamine:

  • Adults and children over 12 years: 5 ml every 6 hours.
  • Children from 6 to 12 years old: from 2 to 4 ml every 6 to 8 hours.
  • Children from 4 to 6 years old: 1.75 to 2 mL every 6 to 8 hours.
  • Children from 2 to 4 years old: 1.25 to 1.75mL every 6 to 8 hours.

Do not give polar amine syrup to children under two years old.


Polaramine is available in the following forms:

  • It extended launch suspension.
  • Extended-release tablet.
  • Oral suspension.
  • Tablet oral.

Components of the polyamine

Polaramine tablets:

Active ingredient:
  • Dexchlorpheniramine maleate 2 mg.
Inactive ingredients:
  • Lactose.
  • Starch-corn
  • Pregelatinized starch.
  • Magnesium stearate.

Polaramine syrup:

Active ingredient:
  • Dexchlorpheniramine maleate 2mg / 5mL.
Inactive ingredients:
  • Sodium citrate.
  • Sodium chloride.
  • Saccharose.
  • Sorbitol (2.8g / 20mL).
  • Methyl hydroxybenzoate
  • Propyl hydroxybenzoate.
  • Bulbs.
  • Ethanol.
  • Water.
  • Shiny scarlet 4R.
  • Apricot flavor.
  • Orange flavor


If you have taken a monoamine oxidase inhibitor (MAOI) such as phenelzine (Nardil), isocarboxazid (Marplan), or tranylcypromine (Parnate) during the past 14 days, do not take this medication.

The mixture of these medications can cause severe adverse reactions.

Talk to your pharmacist before taking other over-the-counter medications for coughs, colds, allergies, or insomnia.

These products may contain medicines similar to polar amine, which could cause an overdose of antihistamines.

Before taking this medication, tell your doctor if you are taking any of the following medications:

  • Medications for anxiety or sleep: such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion).
  • Medications for depression: such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil).
  • Any other medication that makes you feel sleepy or relaxed.

In addition to the drugs mentioned above, others may also interact with a polyamine.

Before taking any prescription or over-the-counter medication, you should talk with your doctor or pharmacist.

Side effects of polyamine

While this medication can rarely cause side effects, sometimes polar amine can cause very serious, and even fatal, side effects if you interact with other not recommended medicines.

Tell your doctor or seek medical attention immediately if you have any of the following signs or symptoms that may be related to a very serious side effect:

  • You can not pass urine or change the amount of urine passed.
  • Seizures
  • Instability.
  • Dizziness or fainting
  • Problems in the view.
  • Signs of an allergic reaction: such as rash, hives, itching, red and swollen skin, tightness in the chest or throat, difficulty breathing, etc.
  • Change in balance
  • Any hematoma or unexplained bleeding.
  • Feeling confused
  • The unusual sensation of tingling, burning, and numbness.
  • Constant sleep
  • Loose stools (diarrhea).
  • Hard stools ( constipation ).
  • Dry mouth.
  • Dry nose
  • I am feeling nervous and excited.
  • No hunger
  • Stomach upset or vomiting
  • Insomnia .
  • I was feeling weak and tired.
  • Thickening of the mucus in the nose or throat.

These are not all the side effects that can occur. If you have questions about side effects, call your doctor.


Symptoms of a polyamine overdose include extreme drowsiness, confusion, weakness, ringing in the ears, blurred vision, dilated pupils, dry mouth, flushing, fever, tremors, insomnia, hallucinations, and possibly seizures.

If you experience any of these symptoms, seek immediate medical assistance.

Precautions with Polaramine

You should not take this medicine if you have taken a monoamine oxidase inhibitor (MAOI) for the past 14 days.

Polaramine is contraindicated in newborns or premature babies and nursing mothers.

As in adults, antihistamines can decrease mental alertness in children, especially young children, producing excitement.

Some diseases can cause susceptibility to the appearance of side effects of the medication.

Take as directed by your doctor or follow the address printed on the product leaflet. Tell your doctor if your condition persists or worsens.