Pirifur: How to Use, Adverse Reactions, Interaction, Precautions and Storage

For the treatment of uncomplicated urinary tract infections caused by gram-negative bacteria. Among the germs sensitive to the drug is Enterobacter spp.

This medicine is an antibiotic used to treat urinary tract infections.

How to use it?

  • This medication works best if taken on an empty stomach one hour or two hours after meals.
  • Take each dose with a full glass of water. If a stomach upset occurs, take it with food or milk.
  • Take this medicine 2 hours before or 2 hours after taking any magnesium, aluminum, or calcium medication.
  • Some examples include quinapril, certain forms of didanosine (buffered chewable tablets, dispersible or pediatric oral solution), vitamins – minerals, and antacids.
  • Also included are sucralfate, bismuth subsalicylate, iron, and zinc.
  • These drugs bind with Pirifur to prevent its total absorption.
  • Antibiotics work best when the amount of medication in your body remains constant.
  • Do this by taking the medication at evenly spaced intervals throughout the day and night.
  • Keep taking this medication until the prescribed amount is completed, even if the symptoms disappear after a few days.
  • Stopping the medication too early may allow the bacteria to continue to grow, resulting in a relapse of the infection.
  • Drinking plenty of fluids while taking this medication is recommended unless your doctor tells you otherwise.

Adverse reactions of the Pirifur

This medicine may cause an upset stomach, loss of appetite, diarrhea, nausea, headache, drowsiness, or dizziness during the first few days as your body adjusts to the medication.

If these symptoms persist or become severe, inform your doctor. Tell your doctor if you have:

  • Restlessness.
  • Changes in the view
  • Mental or mood changes
  • We are ringing in the ears.
  • Convulsions

In the unlikely event that you have an allergic reaction to this medication, seek medical attention immediately.

Symptoms of an allergic reaction include rash, itching, swelling, fever, and trouble breathing. Contact your doctor or pharmacist if you notice other effects not mentioned above.


Tell your doctor if you have:


  • Renal problems.
  • Liver disease.
  • Convulsive disorder
  • Nervous system disorder.
  • The condition of blood vessels.
  • Any allergy.

Exercise caution when driving or performing tasks that require alertness if this medication makes you feel drowsy, dizzy, or dazed. Restrict alcohol consumption.

Because this medication can make you more sensitive to the sun, avoid prolonged exposure to the sun. Wear protective clothing and use sunscreen when outdoors.

Tell your doctor if you are pregnant before using this medicine. This drug is excreted in breast milk. Consult your doctor before breastfeeding.

Interaction with other Drugs

Tell your doctor about all the medicines you can use, with and without a prescription, especially:

  • Warfarin
  • Certain live vaccines.
  • Nitrofurantoína.
  • Quinapril.
  • Didanosine.
  • Vitamins – minerals (e.g., magnesium, aluminum, calcium, iron, zinc).
  • Antacids
  • Sucralfate.
  • Bismuth subsalicylate.

Do not start or stop any medication without the approval of a doctor or pharmacist.

Missed dose of Pirifur

If you miss a dose, take it as soon as you remember it; Do not take it if it is almost time for the next dose; instead, skip the missed dose and resume your usual dosing schedule.

Do not double the dose to catch up. It can present adverse reactions if it exceeds the instructions of the treating specialist.

Go to the nearest Medical Center if you are pregnant and suffer from abnormal symptoms.


Contact the local poison control center or the emergency room if an overdose is suspected. Symptoms of an overdose may include seizures, vomiting, nausea, and unusual slowness.

To consider

  • This medication has been prescribed only for your current condition.
  • Please do not use it later for another infection or give it to someone else. A different medication may be needed in these cases.
  • Piriform can cause false results in some products for the test of diabetic urine (type of cupric sulfate). Consult your doctor or pharmacist for recommendations.


Store at room temperature, away from sunlight and moisture. If your doctor tells you to stop taking Pirifur, throw away any unused medicine.

Piriform loses efficacy over time and should not be saved to treat another infection.