Nalidixic Acid: Uses, Administration, Side Effects, Precautions and Storage

This medication belongs to the family of antibacterials and is used to eliminate urinary tract infections.

The effect is achieved by stopping the production of the proteins that the bacteria need to survive.


Nalidixic acid should be used as directed by the treating physician or according to the instructions found on the medication. To avoid stomach irritation should be taken with food.

When treated with Nalidixic Acid, within 3 hours after the dose, it is not recommended to consume products that have caffeine, magnesium, calcium, aluminum, sucralfate, zinc, or iron, because its components can prevent the drug from taking effect.

To eliminate the infection, the treatment indicated by the attending physician must be followed. Otherwise, the bacteria could be strengthened and not eradicated with the Nalidixic Acid.

Side Effects of Nalidixic Acid

Some medications can cause side effects, either due to excessive use or because the body does not tolerate them. In the case of Nalidixic, the following may be present:

  • Sudden dizziness
  • Drowsiness.
  • Diarrhea or upset stomach
  • Mild or strong headache
  • Rash on the skin.

This medicine can cause allergic reactions such as:


  • Difficulty breathing.
  • Inflammation of the lips, tongue, or face
  • Difficulty focusing your sight or double vision.
  • Rash.
  • Chest tightness.
  • Convulsions
  • Numbness in the extremities of the body.
  • Visualize haloes around light.
  • Weakness in the body
  • Redness on the face or extremities of the body.


This medication sometimes produces drowsiness, blurred vision, or dizziness, so you should avoid activities that require concentration or all active senses when ingested, such as driving, cooking, or a physical sport.

Consuming alcoholic beverages when treated with Nalidixic Acid is harmful to health because it can accelerate or activate side effects.

Nalidixic acid makes the skin sensitive to the sun’s ultraviolet rays, which increases the chances of burns if the body is exposed if protective. The cabins for body tanning have the same effect.

This antibiotic only works against urinary bacteria; its use against viral infections does not work, such as the common cold.

Prolonged or repeated use of Nalidixic Acid can cause a second infection.

This medicine can be harmful to the health of the affected person if:

You have diabetes: it can cause incorrect results on some urine glucose tests.

Pregnancy or breastfeeding: this medicine may cause risks in pregnancy or contaminate breast milk. You can not breastfeed while you are being treated with Nalidixic Acid.

People under 18 should not take this medicine, especially between 3 months and nine years of age.

If the affected person has Alzheimer’s, a central nervous system disease, increased pressure in the brain, hardening of the arteries in his brain, liver problems, heart problems, or severe kidney problems, it is not recommended to take doses of Nalidixic Acid.

Unless the specialist doctor constantly monitors the case until the treatment is finished.

If the medication is expired before consuming a dose, it is recommended to call a specialist and ask if it is appropriate or should be discarded.

The use of this medication should be avoided if:

  • The components of Nalidixic Acid produce severe or detrimental allergies to the individual’s health.
  • The person to be treated suffers from blood diseases such as porphyria or has a history of seizures.
  • If the individual to be treated suffers from cancer and is under chemotherapy under treatment with Melfalán or similar drugs in its composition.
  • If you take an antiarrhythmic medication to achieve an abnormal heartbeat, such as Procainamide, Quinidine, Sotalol, or Amiodarone.

Storage of Nalidixic Acid

Nalidixic acid should be stored at ambient temperature below 25 degrees Celsius or 77 degrees Fahrenheit. It is unnecessary to refrigerate it and can be placed in a hermetically sealed container.

It can not be stored near humidity, heat, or light. Do not store it in the bathroom. Keep Nalidixic Acid out of the reach of children and pets.