Mometasone: Indications, Dosage, Side Effects, Interactions, Precautions and Pharmacology

It is a prescription medicine used to treat asthma, allergies, and skin conditions.

It belongs to a group of medicines called Corticosteroids, more commonly known as steroids.

Mometasone has shown a low risk of primary sensitization and cross-reactions in preliminary patch test studies.

It is a well-tolerated topical glucocorticoid, effective in treating patients with atopic dermatitis, seborrheic dermatitis, psoriasis of the scalp, and psoriasis Vulgaris.

It works by affecting the immune system to decrease inflammation of the respiratory tract, nasal passages, or, if applied topically, the skin.

The medication comes in several forms, including an inhaler, a nasal spray, a cream, a lotion, and an ointment. The nasal spray and the inhaler are used once or twice a day.

Mometasone cream, lotion, and ointment are applied to the skin, usually once a day.


Available brands:

Mometasone can be found in some form under the following brands:

  • Asmanex.
  • Asmanex HFA.
  • Modulate.
  • Elocon.
  • Momexin.
  • Nasonex.
  • Impulse
  • Suniva.


Mometasone is a prescription medication available in several forms that are used to treat a variety of conditions, including:

The nasal spray for nasal allergy symptoms includes nasal congestion, an itchy nose, and sneezing related to allergies. It is also used to treat nasal polyps.

The inhaled form is used to prevent asthma attacks.

The cream, lotion, or ointment treats eczema, psoriasis, atopic dermatitis, and other inflammatory skin conditions.

Mometasone comes in a nasal spray on the nose, usually once or twice a day, depending on whether it is used for allergies or nasal polyps.

The Mometasone inhaler is inhaled into the lungs, usually once or twice daily.

Mometasone cream, lotion, and ointment are applied to the skin, usually once a day. Avoid contact with the eyes.

Spray nasal de Mometasona:

Use Mometasone precisely as prescribed by your doctor.

This medication is only for use in the nose. Do not spray it in your mouth or eyes.

An adult should help a young child to use this medication.

To get the best results, you should continue to use this drug regularly every day without losing a dose. If you miss a dose of Mometasone, take it as soon as you remember.

However, do not take more than the daily dose prescribed by your doctor. Do not use Mometasone more often than prescribed.

To use nasal inhalation, follow these steps:
  • Close one nostril, tilt your head slightly forward and keep the bottle upright while inserting the nasal applicator into the other nostril.
  • For each application, press once firmly on the shoulders of the white applicator with the index finger and the middle finger. Hold the base of the bottle with your thumb.
  • Breathe in gently through the nostril.
  • Breathe through your mouth and repeat in the other nostril.
  • Replace the plastic cap.

Before using a new Mometasona pump for the first time, prepare the pump by spraying ten times or until a fine spray appears. If you do not use the pump for more than one week, re-prime it by spraying twice or until a fine mist appears.


Take Mometasone precisely as prescribed by your doctor. Follow the instructions carefully on your prescription label. Your doctor will finish the best dose for you.

Aerosol nasal:

Treatment of nasal symptoms of allergic rhinitis:

Adults and adolescents (12 years or more): 2 aerosols in each nostril.

Children (2-11 years): 1 spray in each nostril.

The treatment of nasal congestion associated with seasonal allergic rhinitis:

Adults and adolescents (12 years or more): 2 aerosols in each nostril.

Children (2-11 years): 1 spray in each nostril once daily.

Prevention of seasonal allergic rhinitis:

Adults and adolescents (12 years or more): 2 aerosols in each nostril.

Treatment of nasal polyps:

Adults (18 years of age and older): 2 aerosols in each nostril twice daily.



If you have taken too much Mometasone, call your health care provider or the local Poison Center, or seek emergency medical attention immediately.


Store Mometasone between 15 ° and 30 ° C (59 ° to 86 ° F).

When Mometasone Nasal Spray is applied, 50 mcg is removed from its carton, and prolonged exposure of the product to direct light should be avoided.

Short exposure to light, as with regular use, is acceptable.

Side effects

Common side effects include headaches, viral infections, sore throat, and nosebleeds.

The most common side effects of Mometasone nasal spray include:

  • Headache.
  • Viral infection.
  • Sore throat.
  • Nasal hemorrhages.
  • Tos.

Serious side effects:

  • Back pain.
  • Blur or vision loss (occurs gradually if certain products have been used near the eye).
  • Burning and itchy skin with red blisters the size of a pinhead.
  • Elevation of blood pressure.
  • Irregular heartbeat.
  • Irregular menstrual periods.
  • Irritability.
  • Irritation of the skin around the mouth.
  • Loss of appetite
  • Depression.
  • Muscle cramps, pain, or weakness.
  • Nausea.
  • Gain or rapid weight loss.
  • Reddish purple lines (stretch marks) on arms, face, legs, trunk, or groin.
  • Signs of high blood sugar levels (for example, frequent urination, increased thirst, overeating, unexplained weight loss, poor wound healing, infections, fruity breath odor).
  • Changes in skin color.
  • Swelling, burning, cramping, or pain in the stomach.
  • Swelling of the feet or lower legs.
  • Unusual bruises
  • Unusual decrease in sexual desire or ability (in men).
  • Unusual tiredness or weakness
  • Vomiting
  • Weakness of the arms, legs, or trunk (severe).
  • It is worsening infections.

Common side effects of Mometasone inhalers include:

  • Headache.
  • Sore throat.
  • Clogged or snotty nose.
  • Common cold.

Common side effects of the cream, lotion, or ointment forms include reactions at the application site:

  • Ardor.
  • Itch.
  • Irritation.
  • Dryness.

Interactions of Mometasone with other medications:

Mometasone and other medications can affect each other and cause side effects.

This can affect how other medicines work, and other drugs can affect how Mometasone works.

If you are taking other medicines with Corticosteroids for allergy, either orally or by injection, your doctor may recommend that you stop taking them once you start using Mometasone.

There may be an interaction between Mometasone and any of the following:

  • Aldesleukin.
  • Deferasirox.
  • Hyaluronidase.
  • Itraconazole
  • Ceritinib.
  • Other medicines with corticosteroids such as Prednisone, Methylprednisolone, and Dexamethasone.
  • Other nasal sprays

If you are taking any of these medications, talk to your doctor or pharmacist.

Interactions with food:

There are no specific foods that you should exclude from your diet when you take Mometasone.

Mometasone and pregnancy:

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA classifies medications according to safety for use during pregnancy. Five categories: A, B, C, D, and X, are used to classify possible risks to the fetus when a medication is taken during pregnancy.

Mometasone belongs to category C. In animal studies, pregnant animals were given this medication, and some babies were born with problems.


Do not use Mometasone if you are allergic to any of its ingredients.

Taking steroids can put you at higher risk of infections. Mometasone is a nasal steroid and can suppress the immune system.

Oral steroids (those taken by mouth) are more likely to cause immune suppression, but it is possible with Mometasone.

Before taking Mometasone, tell your doctor if you have ever had tuberculosis or a herpetic infection of the eye since Mometasone can worsen these infections by weakening the immune system.

This drug, like all steroids, can decrease the growth rate of children and adolescents.

It can cause glaucoma or cataracts or make these conditions worse.

Avoid chickenpox and measles because you should call your doctor immediately if you are exposed to them while using Mometasone.


Mometasone is a 16 alpha-methyl synthetic analog of beclomethasone; it is classified as a “potent” glucocorticoid for dermatological use.

It is available as a cream, ointment, and 0.1% lotion formulations to treat patients with inflammatory dermatoses that respond to glucocorticoids.

In patients with atopic dermatitis, the effect of 0.1% Mometasone applied once a day for 2 to 3 weeks was similar to other glucocorticoids of equal potencies, such as 0.05% Betamethasone Dipropionate twice a day and Acetone. 0.1% methylprednisolone once a day.

Mometasone at 0.1% was significantly superior to the twice-daily application of less potent glucocorticoids such as clobetasone at 0.05%, hydrocortisone at 1.0%, and hydrocortisone butyrate and hydrocortisone valerate 0.2%.

In patients with seborrheic dermatitis, 0.1% Mometasone was more effective than 2.0% Ketoconazole and 1.0% hydrocortisone in trials lasting 4 or 6 weeks.

In treating psoriasis of the scalp and vulgar psoriasis, 0.1% Mometasone applied once a day for 2 to 8 weeks was generally more effective than other glucocorticoids of similar or weaker potency Betamethasone Valerate 0.1% and Acetonide Fluocinolone 0.025%.

The alternate-day application of Mometasona at 0.1% for two weeks was as practical as a daily application to maintain control of symptoms in a small number of patients with Psoriasis Vulgaris.

Although Mometasone shows a more excellent anti-inflammatory activity and a longer duration of action than Betamethasone, it has a low potential to cause adverse systemic effects, such as suppressing the hypothalamic-pituitary-adrenal (HPA) axis.

In addition, its Atrogenic potential is low and no greater than that of other glucocorticoids in its class, such as Betamethasone Valerate.

Minor to moderate transient local adverse effects have been reported, such as burning, stinging, folliculitis, dryness, acneiform eruptions, and signs of skin atrophy with Mometasone.

In addition to its low potential to cause primary sensitization and cross-reactions with other topical glucocorticoids, Mometasone offers the convenience of daily administration.

Frequent questions

Who should not take this medicine?

Do not use this medicine if you:

  • You are allergic to Mometasone or any ingredient of the medication.
  • You have an active or latent infection of tuberculosis in the lungs.
  • You have an untreated fungal, bacterial, or viral infection.
  • You have an eye infection due to herpes simplex.

In case of infections?

Corticosteroids such as Mometasone nasal spray can worsen existing infections, mask signs of disease, and cause new infections.

If you use this medication for several months or longer, your doctor will check you periodically for signs of infection.

If you have not had chickenpox or measles or have not been vaccinated against these infections, take special care to avoid exposure to them.

Contact your doctor if your symptoms worsen or you have a fever while using this medicine.

Does wound healing affect?

Corticosteroids such as the Mometasone nasal spray can affect the healing capacity of wounds.

If you have ulcers on your nose, have had recent nasal surgery, or have had recent nasal trauma, you should wait until the wounds have completely healed before using this medication.

Use in children?

The Mometasone nasal spray can be used for children 3 to 11 to treat allergic rhinitis and for children 12 and older for acute sinusitis. For the treatment of nasal polyps, the safety and efficacy of this medication have not been established for children.