Klosidol: Uses, Administration, Warnings, Side Effects and Contraindications

It is a narcotic pain reliever. It works in the brain to decrease or relieve mild to moderate pain.

Klosidol administration

Klosidol should be used as directed by a doctor. However, you will find the directions on the medicine package.

It can be taken with or without food. If a stomach upset occurs, it should be taken with food to reduce stomach irritation.

If the patient misses a dose and is taking it regularly, he should take it as soon as possible.

If it is almost time for your next dose, the missed dose should be skipped and returned to your regular dosing schedule. Taking two doses at the same time is not recommended.

Any questions you may have about using Klosidol should be consulted with a doctor.


The medicine may cause drowsiness or dizziness. Therefore, it is not advisable to drive, operate machinery or do anything that could be dangerous until the patient knows how to react to the effects.


Using klosidol alone, with some other medications, or with alcohol may decrease the patient’s ability to drive or perform other potentially dangerous tasks.

Drinking alcohol with klosidol can cause serious side effects. Alcohol consumption should be limited while the patient is taking klosidol.

If the patient drinks alcohol every day, it is not advisable to take klosidol without first talking to a doctor. The combination of klosidol and alcohol can cause liver damage.

The patient must inform his doctor if he is taking tranquilizers, sleeping pills, antidepressants, antihistamines, or any other medicine that may make him sleepy.

Combining the products mentioned above with klosidol can lead to serious side effects, including death.

If the patient experiences dizziness, drowsiness, nausea, or vomiting, it may be helpful to lie down and rest.

Before undergoing medical or dental treatment, emergency care, or surgery, the patient should tell the doctor or dentist that they are using klosidol.

It should be used with caution in the elderly and children because they may be more sensitive to its effects.

The use of klosidol is not recommended in children under 12 years of age. Safety and effectiveness in this age group have not been confirmed.

If the patient is pregnant, she should discuss the benefits and risks of using klosidol during pregnancy with her doctor. Klosidol is excreted in human milk.

If the patient is breastfeeding or will breastfeed while using klosidol, she needs to consult a doctor or pharmacist to discuss the risks to the baby.

When used for long periods or in high doses, klosidol may not work as well and may require higher doses to get the same effect as when it was first taken.

This is known as tolerance. It is recommended to speak with a doctor if klosidol stops are working correctly. The patient should not take more than prescribed.

Klosidol can cause dependence if taken in higher doses than recommended by a doctor or for an extended period.

So it should be taken exactly as prescribed by the doctor.

If the patient suddenly stops taking the treatment, they may experience symptoms such as:

  • Anxiety.
  • Diarrhea.
  • Fever.
  • Runny nose or sneezing.
  • Goosebumps and abnormal skin sensations.
  • Nausea.
  • Pain.
  • Fast heartbeat
  • Stiff muscles
  • See, hear, or feel things that are not there.
  • Tremors
  • Perspiration.
  • Trouble sleeping
  • Vomiting

Klosidol side effects

The patient should see a doctor if any of these more common side effects persist or become bothersome:

The patient should seek immediate medical attention if any of these severe side effects occur:

  • Severe allergic reactions (rash, hives, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue).
  • Anxiety.
  • Cold or clammy skin
  • Confusion.
  • Excessive sweating
  • Hallucinations
  • Loss of appetite
  • Loss of consciousness.
  • Mental or mood changes.
  • Seizures
  • Severe drowsiness or dizziness.
  • Severe or persistent stomach pain.
  • Vision changes
  • Soft spot.
  • Yellowing of the skin or eyes.

However, other effects can arise during the consumption of the drug.

It is recommended that the patient contact a doctor if they have any other symptoms not mentioned in the list that they think may be related to the drug.

How to stop treatment?

It is always advisable to stop taking the drug due to its rebound effect gradually.

It is advisable to contact a doctor as a professional advice is needed in this case regarding health, medications, and other recommendations to give you a stable health condition.

Klosidol contraindications

Some medical conditions can interact with klosidol.

The patient should inform the doctor if he has any medical condition, especially if he presents any of the following situations:

  • If you are pregnant, planning to become pregnant, or are breastfeeding.
  • If you are taking prescription or non-prescription medications, herbal preparations, or dietary supplements.
  • If you have allergies to medicines, foods, or other substances.
  • If you have prostate problems, liver problems, or kidney problems.
  • If you have a history of drug abuse or dependence or depression or if you have ever seriously considered suicide.
  • If you have had a head injury, increased pressure on your brain, growths on your brain, or seizures.
  • If you have inflammatory bowel problems or ulcers, urinary problems, or if you have had abdominal surgery.
  • If you have lung or breathing problems, thyroid problems, heart problems, or specific blood problems (porphyria).

Also, some medicines can interact with Klosidol.

The patient should inform their healthcare provider if they are taking other medications, especially any of the following:

  • Blood thinners because side effects, including an increased risk of bleeding, can be improved with klosidol.
  • Carbamazepine because the risk of severe side effects and toxicity can occur, including nausea, vomiting, loss of coordination, and involuntary eye movements.
  • Antidepressant medications, anticonvulsants, barbiturate anesthetics, cimetidine, HIV protease inhibitors, and terfenadine may increase side effects.
  • Naltrexone because the effectiveness of klosidol may decrease.
  • Sodium oxybate due to side effects, which include an increased risk of sleep duration and drowsiness leading to unresponsiveness and coma, may be increased.

This may not be a complete list of all interactions that can occur.

So it is necessary to ask a doctor if klosidol can interact with other medications that the patient takes.

Klosidol during pregnancy and lactation

The patient must consult a doctor for a recommendation since this case requires special attention.

The patient should explain her condition and condition to a doctor so that he can prescribe it properly.