Hepasil: Composition, Indications, Mechanism of Action, Contraindications, Precautions, Dosage and Benefits

The liver performs many essential functions.

Supporting our natural detoxification processes is more critical than ever in an increasingly toxin-laden world than supporting our natural detoxification processes. It plays a vital role in the proper functioning of the body.

Liver malfunction causes jaundice, anemia, swelling of the hands and feet, liver enlargement and inflammation, heartburn, poor digestion, and irritation of the urinary bladder.

Hasil contains hepatoprotective herbal ingredients that protect the liver from viruses and other microbes and excrete toxins.

It is formulated with USANA intelligence technology to unlock cellular communication codes with proprietary nutrient blends that activate the naturally protective detoxification processes of liver cells.

Intelligence Detox-Support Complex offers a wide range of phytochemicals, including USANA’s patented green tea extract, milk thistle extract, broccoli concentrate, and olive (olive extract).

With two patents pending, Hepasil’s hybrid technology enables USANA to formulate a truly unique supplement that gives your liver what it needs to function at optimal levels.


It uses patent-pending nutritional hybrid technology, allowing USANA to make a truly unique and complete liver support supplement by safely combining incompatible but equally essential nutrients in one two-layer tablet.


The liver is the body’s primary detoxifying organ. Glutathione, a powerful antioxidant secreted in the body, and vitamin C, are involved in detoxification pathways.

Milk thistle extract supports liver cell health and scavenges free radicals. N-acetyl l-cysteine ​​is a glutathione precursor.

Alpha-lipoic acid influences glutathione production and supports phase II detoxification reactions.

Olivia, the proprietary olive fruit extract, broccoli extract, green tea extract, and turmeric, is excellent antioxidant support. This is crucial for liver health because the detoxification process generates many harmful free radicals.

Including Hepasil as part of a healthy lifestyle can help maintain healthy liver function and balance the body’s natural detoxification processes.

The science behind Hepasil

Choline is a critical ingredient in the liver that helps metabolize fats and cholesterol and remove them from the liver. Choline is oxidized to betaine upon entering the cell, which donates the methyl groups necessary for healthy detoxification reactions.

The liver uses biotin to support macronutrient metabolism and glycogen synthesis for energy.

In addition to alpha-lipoic acid and n-acetyl l-cysteine, the InCelligence Detox Support Complex in Hepasil also offers a wide range of phytochemicals such as green tea extract, milk thistle extract, broccoli concentrate, and olive tree patented by USANA.

These powerful nutrients target a cell signaling pathway that supports natural protective processes within a healthy liver:

I am balancing detoxification reactions by stimulating the production of phase II detoxification enzymes, including glutathione-S-transferases.

These enzymes bind to highly reactive metabolites, the product of a metabolic reaction, generated in the liver during phase I and convert them into a form that can be excreted from the body.

Defense against oxidative stress caused by free radicals generated during phase I acting as direct antioxidants.

The nutrients also activate the production of endogenous antioxidants produced in the body, including glutathione, which is more concentrated in the liver.

The formula is patent pending for its ability to increase glutathione, its antioxidant capacity for vitamin C, and the detoxification activity that it helps to produce in the body.

What effect does Hepasil have on cell signaling?

Hasil contains a unique blend of ingredients that optimize cell signaling pathways related to glutathione production.

This process supports the body’s natural detoxification and antioxidant capacity by increasing plasma glutathione and vitamin C levels.

Composition of Hepasil

Hasil is used to treat liver dysfunction. It can also be used as complementary medicine to treat chronic inflammatory diseases such as cirrhosis, liver toxicity, and liver damage.

  • Choline bitartrate.
  • Alpha-lipoic acid.
  • Turmeric extract.
  • Milk thistle extract.
  • Olivia.
  • Green tea extract.
  • Biotin.

We mention milk thistle extract (also known as milk thistle extract) 150 grams, one of the active ingredients in Hepasil, which supports the liver; it is called silymarin, a chemical extract from the seeds of milk thistle that acts as a potent antioxidant.

This main ingredient is one of the most powerful antioxidants currently known. Lecithin as powdered soy lecithin is present at 100mg and inositol at 200mg. And a set of B vitamins:

  • Thiamine 30 mg.
  • Riboflavin 30 mg.
  • Niacinamide 30 mg.
  • Pyridoxine 30 mg.
  • Vitamin B-12 4.8 mcg.
  • Calcium 36 mg.
  • Magnesio 58 mg.
  • Choline 58 mg.

Hasil is a carefully formulated blend of antioxidants designed to support and maintain the body’s second-largest organ – the liver.

Other important antioxidants present in Hepasil are Alpha Lipoic Acid, Green Tea Extract, Turmeric Extract, and Olivia, the proprietary olive fruit extract.

Each helps protect multiple enzyme systems in the liver and provides secondary antioxidant protection to the rest of the body.

Adding a supplement like Hepasil to your healthy lifestyle is a great way to help maintain healthy liver function. It can also help support your body’s natural detoxification processes.

Indications of Hepasil

Hasil suspension is indicated as a complementary therapy in treating the liver disease of various etiologies; acute hepatitis, persistent chronic and aggressive chronic hepatitis, cirrhosis of the liver, fatty liver, and toxic or metabolic liver damage.

It has been shown to protect the liver from damage caused by general anesthesia. Hasil promotes healthy liver function, and the In Celligence Detox and Support Complex offers a highly effective combination of nutrients that actively support the body’s natural protective processes.

These processes include stimulating the production of phase II detoxification enzymes, including glutathione-S-transferases, and activating the body’s endogenous antioxidant production, such as glutathione, which is more concentrated in the liver.

Hasil’s mode of action

Hasil restores the functional efficiency of the liver by protecting the liver parenchyma and promoting hepatocellular regeneration.

The antiperoxidative activity of Hepasil prevents the loss of functional integrity of the cell membrane, maintains cytochrome p-450, accelerates the recovery period, and ensures the early restoration of liver functions in infectious hepatitis.

Hasil facilitates the rapid elimination of acetaldehyde, the toxic intermediate metabolite of alcohol metabolism, and ensures protection from alcohol-induced liver damage.

Hasil decreases lipotropic activity in chronic alcoholism and prevents fatty infiltration of the liver.

In pre-cirrhotic conditions, Hepasil stops the progression of the disease and prevents further liver damage.

Hasil improves appetite, digestion, and assimilation processes and promotes weight gain as a daily health supplement.

Hasil clinical pharmacology

Hasil works by stabilizing the cell membranes of the liver, thus reducing their permeability to certain toxic substances.

This stabilization can occur due to a competitive inhibition between Hepasil and hepatoxic substances at the cell membrane level.

The pharmacological tests indicate that Hepasil protects liver cells from damage induced by agents (alcohol, carbon tetrachloride, general anesthetics).

It is known to have destructive effects on liver cells. Published clinical data demonstrate that Hepasil is safe and well-tolerated.

When administered as add-on therapy to patients with various liver diseases, Hepasil improves clinical and biochemical parameters.

Hepasil contraindications

Hasil is contraindicated in people with hypersensitivity to the product or when there are mechanical obstacles in the bile ducts.

Before using this medicine, notify your doctor if:

  • You are allergic to any food, drug, or substance; the patient is under 18 years of age, has a hormonal disorder, is taking prescription or over-the-counter medications, is pregnant or planning to become pregnant, or is breastfeeding.

Hasil precautions

No conditions have been found that would prevent the administration of Hepasil. Some minor allergic reactions include diarrhea, a bloated feeling, a rash, and itching.

However, contact your healthcare professional immediately if you experience any side effects that persist or cause any discomfort.

Pregnancy and breastfeeding

Hasil has not been reported to alter normal pregnancy, and there has been no evidence of toxicity in the embryo. There is no evidence of poor development in the breastfed infant.

Adverse reactions

Hasil is usually well tolerated, even when the doctor tries to administer it for long periods. In high doses, a slight laxative and diuretic effect can be observed.

Hasil dosage

In children, the dosage is 5 ml (one teaspoon), and in adults, the dosage is 10 ml (two teaspoons) three times a day or as directed by the doctor. The usual dose in adults can also be 140 mg 2-3 times a day.

The dosage of this medication should ideally be prescribed by your supervising physician based on your age, general medical history, and current condition.

Taking three Hepasil tablets per day for 28 days can significantly help optimize natural glutathione production and overall antioxidant capacity.


  • Keep in a cool and dry place.
  • Protect from heat and light.

The benefits of Hepasil

Your liver is vital to maintaining good health. Almost all the nutrients you eat, foods, beverages, medications, and supplements go through your liver. That is where the nutrients are broken down so that your body can use, transform and eliminate them from your system.

Hasil is fortified with USANA InCelligence Technology to support healthy liver function in many ways and provide the body with nutrients that promote the natural detoxification process and endogenous antioxidant activity.

Medical studies with Hepasil

Scientists at USANA headquarters have conducted a double-blind controlled study to test the effectiveness of Hepasil.

Study results showed that circulating glutathione and vitamin C levels increased after Hepasil supplementation.

This is the first time that a combination of essential nutrients and phytochemicals has been shown to increase plasma levels of vitamin C and glutathione simultaneously.

The results also showed that the recommended dose of Hepasil can increase levels of glutathione and vitamin C, essential molecules for antioxidant defense, and support natural detoxification pathways/processes.

The study also looked at whole blood glutathione and vitamin C (GSH) levels. The purpose was to evaluate the effectiveness of Hepasil in increasing the levels of total blood glutathione and vitamin C.

The results showed that Hepasil significantly increased plasma whole blood glutathione only eight hours after supplementation during the chronic, acute phase.

It also increased plasma levels of vitamin C just two hours after the first supplementation, maintained throughout the acute phase.

To demonstrate the clinical benefit of the observed increases in glutathione and vitamin C, USANA scientists determined the antioxidant capacity of each subject’s blood.

They used the serum antioxidant reserve test (SAR) developed by USANA Health Sciences. They found that subjects supplemented with Hepasil were significantly more resistant to oxidative damage than subjects who received the placebo.

This proprietary combination of essential nutrients and broccoli extract, milk thistle, and alpha-lipoic acid simultaneously increase plasma levels of vitamin C and glutathione. It activates the molecular machinery necessary to use glutathione in detoxification reactions.

It also significantly increases the overall ability of the blood to protect against oxidative damage.

At the same time, these results show that taking the recommended dose of Hepasil increased the body’s natural detoxification and antioxidant capabilities by increasing glutathione and vitamin C levels.

Can a detox help your liver?

You want to do everything you can to take an active role in your health. But if you think you need a liver detox (also known as liver flushing or cleansing), you should know that it is not much it can do for you.

Your liver is one of the largest organs in your body. Helps remove waste products and processes various nutrients and medications.

Most people think that a cleanse will help your liver better remove toxins after too much alcohol or unhealthy foods.

Some hope it helps their liver work better daily. Many believe that it will help treat liver disease.

Like most detoxification methods, a liver cleanse has specific steps. You may have to fast or drink juices or other fluids for several days.

You may need to eat a restricted diet or take herbal or dietary supplements. Some detoxes also prompt you to purchase a variety of other commercial products. Some approaches can combine several of these methods.

Is there any proof that liver detoxification works?

There is no scientific proof that cleanses and removes toxins or makes you healthier. Detox diets can make you feel better because they generally don’t allow you to eat highly processed foods.

These foods contain solid fats and processed sugar. They are high in calories but low in nutrition. Detox diets can also cut down on foods you might be allergic to or sensitive to, such as dairy, gluten, eggs, or peanuts.

Doctors say that liver detoxification is not essential to your health or how well your liver works. There is no evidence that they help eliminate toxins after overeating food or alcohol.

There is also no evidence that they repair liver damage that has already occurred.

Does milk thistle help your liver?

Milk thistle is an herb that contains a compound called silybin. You may have heard that it helps your liver work better and can help treat liver disease.

But, just as there is not enough evidence that liver detoxification works, there is not enough to show that milk thistle or its extracts make your liver healthier.

There is some evidence that compounds in milk thistle have helped improve certain types of liver disease symptoms. But no studies show that it treats the disease itself.

Is liver detoxification safe?

There are medical treatments for various liver diseases. But nothing shows that detox programs or supplements can repair liver damage. Detoxes can damage your liver. There are also things you need to know about these programs and products:

Some companies use ingredients that could be harmful. Others have made false claims about how well they treat serious illnesses.

Unpasteurized juices can make you sick, especially if you are older or have a weakened immune system.

If you have kidney disease, a cleanse that includes large amounts of juice can worsen your condition.

If you have diabetes, check with your doctor before considering any diet that changes the way you usually eat.

If you need to fast as part of a detox program, you may feel weak, pass out, have headaches, or become dehydrated. If you have hepatitis B that has caused liver damage, fasting can worsen the injury.

How to keep your liver healthy

Your general health and your genes affect your liver.

The same goes for diet, lifestyle, and the environment. You can take simple, common-sense steps to help keep your liver healthy without special detox programs.

These guidelines can be essential if you have certain things that make the liver disease more likely, such as heavy alcohol use or a family history of liver disease.

  • Limit the amount of alcohol you drink. Talk to your doctor about what is suitable for you.
  • Eat a well-balanced diet every day. That’s 5-9 servings of fruits and vegetables and fiber from vegetables, nuts, seeds, and whole grains. Also, include protein to support the enzymes that help your body detox naturally.
  • Maintain a healthy weight, or lose weight if you need to. Exercise every day if you can. Check with your doctor if you haven’t been active.

Reduce risk behaviors that can lead to viral hepatitis:

  • Avoid illegal drugs, but if you do use them, don’t share needles or straws to inject or snort them. Don’t share razors, toothbrushes, or other household items.
  • Just tattoos from a sterile shop. Don’t have unprotected sex with strangers. Contact your doctor if you think you may have some problem with your liver or complications from your condition.