It is used in people whose cholesterol levels are too high and when diet alone cannot lower these levels adequately.
Ezetrol helps lower cholesterol levels .
Ezetrol can be taken alone or with other cholesterol-lowering medications. These medications are known as hmg-coa reductase inhibitors (or statins), in addition to diet.
In people who have high levels of plant sterols in their blood (what doctors call sitosterolemia), ezetrol helps lower these levels.
Cholesterol is one of several fatty substances found in the bloodstream. Your total cholesterol is made up mostly of LDL and HDL cholesterol.
LDL cholesterol is often called “bad” cholesterol because it can build up on the walls of your arteries to form plaque. Eventually, this plaque buildup can lead to narrowing of the arteries.
This narrowing can slow or block blood flow to vital organs such as the heart and brain. This blockage of blood flow can lead to a heart attack or stroke.
HDL cholesterol is often called “good” cholesterol because it helps keep bad cholesterol from building up in your arteries and protects against heart disease.
Triglycerides are another form of fat in the blood that can increase your risk of heart disease.
How does ezetrol work?
Ezetrol lowers high total cholesterol, LDL (bad) cholesterol, and triglycerides, and increases HDL (good) cholesterol.
Ezetrol works by decreasing the absorption of cholesterol in the small intestine. Statins lower cholesterol in a different way, by reducing the amount of cholesterol made in the liver.
Ezetrol adds to the cholesterol lowering effect of statins.
For patients with heart disease and a history of a heart attack or hospitalization for unstable angina (chest pain), ezetrol combined with cholesterol-lowering drugs called statins reduces the risk of heart attack, stroke, surgery to increase blood flow cardiac arrest or hospitalization for chest pain.
Your doctor may have prescribed ezetrol for another reason. Ask your doctor if you have any questions about why ezetrol has been prescribed for you.
Ezetrol is not addictive.
Use in children and adolescents
Ezetrol is used in children and adolescents (ages 10-17) to treat familial hypercholesterolemia, a type of high cholesterol that runs in families (that is, it runs in families).
Ezetrol is not recommended in children under 10 years of age, as very few studies have been done on its effects in these children.
Your doctor will evaluate whether ezetrol is suitable for your child. Depending on your child’s pubertal development, ezetrol may not be right for him or her.
Before taking ezetrol
But ezetrol is:
- The packaging is torn or shows signs of tampering.
- The expiration date on the package has passed. If you take this medicine after the expiration date, it may not work.
- You are allergic to ezetrol or any of its ingredients.
Symptoms of an allergic reaction can include:
- Short of breath.
- Swelling of the face
- Tongue or throat
Do not take ezetrol together with a statin if:
- You have active liver disease.
- You are pregnant or breastfeeding.
Do not take ezetrol together with fenofibrate if:
- You have gallbladder disease.
If you are not sure whether you should start taking ezetrol, talk to your doctor.
Tell your doctor if:
- You are pregnant or intend to become pregnant.
- If it is necessary to consider using ezetrol during pregnancy, your doctor will discuss the risks and benefits of taking it.
- You are breastfeeding.
- It is not known if ezetrol passes into breast milk.
- You have or have had any medical conditions, including liver disease or liver problems.
- If you are prescribed ezetrol with a statin, your doctor will do a blood test to make sure you do not have problems with your liver.
- You have any allergies to any other medicine or any other substance, such as foods, preservatives, or dyes.
- If you have not told your doctor about any of the above, tell them before taking any ezetrol.
- If you are taking other medications.
Tell your doctor if you are taking any other medicines, including medicines you buy without a prescription from your pharmacy, grocery store, or health food store.
Some medications should not be taken with ezetrol, including:
Certain fibrate medications used to lower cholesterol levels, for example gemfibrozil. However, the fibrate drug fenofibrate can be taken with ezetrol.
Your doctor or pharmacist has more information on medicines to be careful with or avoid while taking ezetrol.
Some medications and ezetrol can interfere with each other, including:
- Bile acid sequestrants, such as cholestyramine, used to lower cholesterol levels.
- Cyclosporine, used to suppress the immune system.
- Warfarin or fluindione, used to prevent blood clots.
These medications can be affected by ezetrol, can affect the way it works, or can increase the risk of side effects with ezetrol.
You may need different amounts of your medicine, or you may need to take different medicines or take your medicines at different times.
Your doctor or pharmacist has more information on medicines to be careful with or avoid while taking ezetrol.
How to take it
- Take ezetrol only when prescribed by your doctor.
- The recommended dose is 10 mg once a day, at any time of the day.
- Swallow ezetrol with a glass of water.
- Follow all instructions given by your doctor and pharmacist carefully. They may differ from the information in this brochure.
- If you do not understand the instructions, ask your doctor or pharmacist for help.
When to take it
Ezetrol can be taken at any time of the day.
It does not matter if you take ezetrol with or without food. However, take it around the same time each day. Taking ezetrol at the same time each day will have the best effect. It will also help you remember when to take your dose.
Your doctor may ask you to take ezetrol with other cholesterol-lowering medications, such as statins, to help you better control your cholesterol.
If you are taking a statin, ezetrol can be taken at the same time as the statin.
If you are taking a bile acid sequestrant, such as cholestyramine, take your ezetrol at least two hours before or four hours after taking the bile acid sequestrant.
How long to take it
Ezetrol helps lower your cholesterol. It does not cure your condition.
Therefore, you should continue taking it as directed by your doctor if you hope to lower your cholesterol and keep it low.
You may need to take cholesterol-lowering medicine for the rest of your life. If you stop taking ezetrol, your cholesterol levels may rise again.
If you miss a dose of ezetrol
If it is almost time for your next dose, discard the missed dose and take the next dose when it is due. Otherwise, take it as soon as you remember, and then go back to taking your tablet (s) as you normally would.
If you are not sure about skipping your dose, talk to your doctor or pharmacist.
Do not take a double dose to make up for a missed dose.
If you have trouble remembering to take your tablets, ask your pharmacist for some advice.
If you take too much ezetrol (overdose)
Call your doctor or go to the nearest hospital or emergency medical center right away if you think you or anyone else may have taken too much ezetrol. Do this even if there are no signs of discomfort or poisoning.
While using ezetrol
Things you should do:
- If you become pregnant while taking ezetrol, tell your doctor.
- Have your blood fats checked when your doctor tells you to, to make sure ezetrol is working.
- Even if you are taking medicine to treat high cholesterol, it is important to have your cholesterol checked regularly. You also need to know your cholesterol levels and goals.
- If you are about to start any new medicine, tell your doctor and pharmacist that you are taking ezetrol.
- If you are prescribed ezetrol with a statin, your doctor will do blood tests to check for problems with your liver.
Things you should not do:
Do not give ezetrol to anyone else, even if they have the same condition as you.
Things to watch out for:
Be careful driving or operating machinery until you know how ezetrol affects you. Side effects have been reported with ezetrol that may affect your ability to drive or operate machinery. Individual responses to ezetrol can vary.
Treatment for high cholesterol
High cholesterol can be treated in two main ways:
Changes in lifestyle
This includes a diet to lower cholesterol, increase physical activity, and control weight. Consult your doctor before increasing physical activity.
Cholesterol-lowering medications are used in conjunction with lifestyle changes to help lower cholesterol.
Tell your doctor or pharmacist as soon as possible if you do not feel well while taking ezetrol.
Ezetrol helps most people with high cholesterol, but it can have unwanted side effects in some people.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you experience some of the side effects.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor immediately or go to an accident or emergency at the nearest hospital if you notice any of the following symptoms:
- Swelling of the face, lips, mouth, throat or tongue that may cause difficulty in swallowing or breathing.
These can be serious side effects. If you have them, you may have had a severe allergic reaction to ezetrol. You may need urgent medical attention or hospitalization. These side effects are very rare.
Tell your doctor immediately if you notice any of the following symptoms:
- Skin rash and hives.
- Raised red rash, sometimes with target-shaped lesions.
- Dark colored urine.
- Light-colored bowel movements.
- Yellowing of the skin and eyes.
- Joint pain
- Bleeding or bruising more easily than normal.
- Constant abdominal pain with nausea and vomiting.
These can be serious side effects. You may need urgent medical attention. Serious side effects are rare.
Tell your doctor immediately if you notice the following:
Unexplained muscle aches, tenderness, or weakness, not caused by exercise.
This can be a serious side effect. This is because in rare cases, muscle problems can be serious, including muscle breakdown leading to kidney damage. You may need urgent medical attention.
Other side effects not mentioned above can also occur in some patients. Tell your doctor if you notice any other effects.
In addition, the following side effects have been reported with the use of ezetrol:
- Wind or excess gas in the stomach or intestines.
- Decreased appetite.
- Dry mouth.
- Abdominal pain.
- Inflammation of the pancreas.
- Tingling or numbness in the hands or feet.
- Inflammation of the gallbladder
- Elevations in some laboratory blood tests of liver or muscle function.
- Unusual tiredness or weakness
- Muscle spasms.
- Neck Pain.
- Chest pain.
- Pain in arms and legs.
- Back pain.
- High blood pressure
- Swelling, especially in the hands and feet.
In adolescent patients (10 to 17 years of age) there have been no studies for more than a year on the effect of taking ezetrol in combination with simvastatin on bone development, growth, social and emotional development or fertility.
Don’t be alarmed by these lists of possible side effects. You cannot experience any of them.
Keep your tablets in the blister until it is time to take them. If you take the tablets out of the blister, they may not keep well.
Keep ezetrol in a cool, dry place where the temperature stays below 30 ° C. Do not store it or any other medicine in the bathroom or near a sink.
Do not leave it in the car or on window sills. Heat and humidity can destroy some medicines.
Keep it where children cannot reach it. A closed cupboard at least one and a half meters above the ground is a good place to store medicine.
If your doctor tells you to stop taking ezetrol or that the tablets have expired, ask your pharmacist what to do with any of the leftover medicines.