Ezetimibe: Administration, Side Effects, Precautions, Interactions, Recommendations and Storage

It is a drug used to reduce cholesterol levels in the body, thus preventing possible heart attacks or strokes.

According to the affected conditions, Ezetimibe can be used accompanied by a diet low in fat and cholesterol, as with other medications such as statins or fibrates.


For its full effectiveness, it must be taken orally as directed by the attending physician, usually once a day, accompanied or not by food. Everything depends on the condition and the body’s results from the treatment.

Most people with high cholesterol do not have alarming symptoms or are easily recognized; the drug should not stop even if the person in treatment sits in their full physical and mental faculties.

If the daily dose is stopped, it is possible that the disease is not fully cured, and you have to take the medication further or take other alternatives to overcome the case satisfactorily.

Side effects

There is a risk that Ezetimibe, together with the Statin, will cause damage to the body or even muscle damage if taken together with Fibrate; there is also the possibility that the body does not absorb all the components of Ezetimibe if it is ingested together with the medications above.

If the patient is taking Ezetimibe, Statin, and Fibrate and has the following symptoms, you should stop using them or contact your treating doctor immediately to determine the cause of the condition:


  • Nausea crowded.
  • Persistent vomiting
  • Severe abdominal pain or stomach pain.
  • Yellowish skin and eyes.
  • Muscular weakness.
  • Sensitivity in the skin.
  • Pain in the extremities of the body.
  • Fever without showing signs of infection.
  • Dark urine.

In some cases, this drug can produce an allergic reaction, and the symptoms are usually:

  • Inflammation in the face, throat, lips, or tongue.
  • Rash on the extremities of the body.
  • Redness of the skin.
  • Itching or burning in the skin.
  • Difficulty breathing.
  • Acceleration of the heart rate.
  • Intense dizziness


Ezetimibe is not recommended during pregnancy or if it is in the process of breastfeeding unless it is strictly necessary and guided by a medical specialist because the dosage can be passed to the baby through breast milk.

If a person in treatment with Ezetimibe should undergo surgery, it is recommended to indicate to the doctor the daily dose of the drug to prevent any future complications.


Ezetimibe can change its effect or effectiveness with some medications or even increase the risk of suffering side effects in the short or long term.

Before undergoing treatment with Ezetimibe, anyone should tell their treating doctor the rest of the medicines they are consuming to assess if any can cause in conjunction with Ezetimibe any harmful health problems.

Because it is a specific medicine to attack high cholesterol problems, you can not increase the dose deliberately or suspend its use without the previous indication of your treating doctor.


The intake of alcoholic beverages should be avoided while being treated with Ezetimibe because it may cause counterproductive effects on the individual’s health.

To accelerate the effectiveness of the drug, the body should be helped with a diet low in cholesterol and saturated fats and maintain a rigorous medical control and acquire a daily exercise routine.

Ezetimibe is only prescribed for people who suffer from high cholesterol. It should not be shared with other people who do not have this medication prescribed by a specialist.

It is essential to develop laboratory tests periodically to determine the effectiveness of the treatment and monitor progress, as well as tests of the liver functioning of the body.


This medicine should be kept at ambient temperature, always away from moisture, heat, or sunlight. It is not necessary to refrigerate it.

Under no circumstances can it be stored near the reach of children or pets.

Suppose the medication is expired before being discarded. In that case, you should ask the attending physician if it can still be ingested for a reasonable time or if your dose should be discarded immediately to prevent future problems or side effects.