Estradiol: Uses, Administration, Side Effects, Precautions and Storage

It is known as a female hormone that is prescribed to women who are in the menopausal period to reduce symptoms.

These symptoms are usually somewhat uncomfortable or annoying for those affected, such as:

  • Vaginal dryness
  • Hot flushes.
  • Vaginal tenderness
  • Irritation.

These symptoms are caused by the body producing less estrogen . It is recommended to first use creams or products that are applied in and around the vagina before ingesting them orally, because they are absorbed faster by the skin, which generates relief or improvements in less time.

Before starting treatment with drugs containing estrogen, the doctor will prescribe drugs such as:

  • Bisphosphonates.
  • Raloxifeno.
  • Alendronate.

They help prevent bone loss and are often safer during or after menopause.

Medications such as Estradiol that contain estrogen are also often used by women who have conditions such as:

Which decreases the body’s natural production of estrogen.

These drugs can also be used by patients, whether men or women, who suffer from certain types of cancer, such as:

  • Breast cancer spread to other places in the body.
  • Prostate cancer.

Administration of Estradiol

Before undergoing hormonal treatment with Estradiol, the patient should carefully read the indications on the package or brochure supplied by the pharmacist and clarify any doubts that may arise with her doctor.

Estradiol should be ingested with or without food, but it is recommended after meals or meals to prevent uncomfortable stomach upset.

This medication should be used once a day or as directed by the treating physician. The patient should under no circumstances decrease or increase the dose without first consulting a specialist, since this can generate serious side effects.

The dosage can be increased by the doctor if the condition does not improve. To guarantee the effectiveness of the treatment, the patient should take the medicine at the same time every day indicated by the specialist.

The extended-release tablets should not be crushed or crushed, as this may cause all of the medication to be lost or released, resulting in or increasing side effects.

The extended-release tablets can only be chopped if they have a dividing line and if the doctor gave the order.

Side effects

The most common symptoms that this drug generates before the body adapts to the dosage are:

  • Tender breasts.
  • Stomach ache.
  • Weight changes
  • Sickness.
  • Headache.
  • Vomiting

It is not common for Estradiol to generate side effects related to allergic reactions, however the patient should be attentive if they present the following symptoms:

  • Itching in the extremities of the body.
  • Swelling around the eyes, mouth, throat, and tongue.
  • Rash on the body.
  • Difficulty breathing.
  • Whistling when inhaling.
  • Severe dizziness

There have been no cases where this drug causes serious side effects, but if the patient has the following symptoms, they should contact their doctor or go to the nearest health center:

  • Unusual vaginal bleeding
  • Depression .
  • Hemorragia intermenstrual.
  • Memory loss.
  • Vaginal discharge with the presence of blood.
  • Increase or appearance of vaginal irritation.
  • Prolonged and recurrent bleeding.
  • Stomach or abdominal pain
  • Chronic vaginal itching, burning, odor, pain, or discharge.
  • Persistent vomiting
  • Dark urine
  • Sickness.
  • Swelling of the hands or feet
  • Increased thirst.
  • Yellowish skin or eyes

Estradiol may cause the following symptoms from blood clots:

  • Strokes
  • Heart attacks.
  • Pulmonary embolism
  • Deep venous thrombosis.

If the patient begins to present several of the following symptoms, she should stop treatment and immediately contact her doctor or go to a nearby health center, hospital or clinic:

  • Unusual sweating
  • Pain located in the chest.
  • Sudden headache
  • Pain in the left arm.
  • Muscle or one-sided weakness.
  • Difficulty focusing on objects at short or long distances.
  • Confusion.
  • Partial or complete blindness.
  • Difficulty speaking
  • Swelling in the legs.
  • Cramps in the arms and legs.
  • Numbness in the arms.
  • Body weakness
  • Coughing up blood
  • Sudden fainting spells
  • Constant dizziness

Precautions

The patient should tell the doctor before undergoing treatment if she has suffered from:

  • Cancer of the breast, uterus or ovaries.
  • Vaginal bleeding from unknown cause.
  • Blood clots.
  • Some heart disease
  • Stroke
  • Renal disease.
  • Liver diseases
  • Blood clotting disorders.
  • Diabetes.
  • High blood pressure.
  • Thyroid disease.
  • Obesity.
  • Lupus.
  • Hormonal problems
  • Mineral imbalance.
  • Fibroids or endometriosis.
  • Seizures
  • Gallbladder disease
  • Asthma.
  • Blood disorders
  • Migraines
  • Mental disorders.

The patient will not be able to smoke while being treated with Estradiol, because the substances in tobacco increase the risk of suffering from:

  • High blood pressure.
  • Stroke
  • Heart attacks.
  • Blood clots.

This medicine could generate sudden spots on the skin or face, with a dark hue, so the patient should be kept away from sunlight, because exposure to the sun without protection could increase or worsen this effect.

The use of:

  • Solar lamps.
  • Tanning booths.

Under no circumstances can this medicine be used during pregnancy, as it can affect the normal development of the fetus. If the patient suspects her condition, she should notify her physician immediately.

Storage

This medicine should be stored at room temperature, in a space free from moisture, heat and away from sunlight.

It cannot be within the reach of children or household pets, because its use without a medical prescription can have harmful effects on the health of the affected person.