Espaven: Uses, Warnings, Precautions, Dosage, Side Effects, Interactions and Storage

It is a medicine that increases the movements or contractions of the stomach and intestines.

This medication is also used to treat or prevent reflux and relieve symptoms such as nausea, vomiting, a continued feeling of fullness after meals, and loss of appetite.

Also, espaven can improve feeding problems and regurgitation. Metoclopramide can be used to prevent nausea and vomiting caused by other medications.

The active substance in espaven is metoclopramide. Metoclopramide is a tablet, liquid, and injection (given with a needle).

Warnings and cautions

Before administering medication

Metoclopramide should not be taken if you have had an unusual or allergic reaction to metoclopramide or an ingredient in the formulation.

Talk to your doctor or pharmacist if the patient has the following conditions. Precautions should be taken with this medicine if you have:

  • Seizures
  • Pheochromocytoma (tumor in the adrenal gland).
  • Gastrointestinal bleeding.
  • Ulcer or blockage in the gastrointestinal tract.

Dosing conditions

  • Give this medication exactly as your doctor tells you.
  • Give the medicine simultaneously every day unless your doctor tells you otherwise.
  • If the patient is taking liquid medications, carefully measure the liquid doses. Use an oral syringe or medicine spoon provided by your pharmacist.
  • When espaven is used to prevent nausea and vomiting caused by other drugs (such as anticancer drugs), the drug can be given through a vein.

What to do for a missed dose

Give the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose. Give the next dose at the usual time.


Do not give a double dose to make up for a missed dose.

Side effects

Side effects while taking metoclopramide can be:

  • Dizziness.
  • Drowsiness.
  • Restlessness.
  • Fatigue.
  • I sleep more than usual (babies cannot wake up to feed).
  • Watery bowel movements (diarrhea).
  • Difficulty having a bowel movement (constipation).

Check with your child’s doctor if you continue to have any of these side effects and they do not go away or if they bother you.

Other effects for which calling a doctor immediately.

  • Inability to sleep
  • Unusual dryness in the mouth.
  • Unusual irritability
  • Bleeding menstrual periods (in girls) that are not normal, such as shorter periods than usual or at a different time of the month.
  • Breast pain or swelling (in boys or girls).

Go to the emergency room if you have any of these side effects.

  • Muscle spasms (especially of the head, face, and neck).
  • Shaking of the hands
  • Sudden movements of the arms, legs, or eyes.
  • Changes in mood or behavior.
  • Skin rash, hives, itching.
  • Difficulty breathing.
  • Swelling of the hands, feet, or face.

Security measures

This medicine may make the patient dizzy, sleepy, or less alert than usual. If you have activities that require your attention, take appropriate precautions.


Some medicines should not be taken together with metoclopramide; in some cases, the dose of metoclopramide or another medicine may need to be adjusted.

It is important to tell your doctor and pharmacist if you take any other medications (prescription, over-the-counter, or herbal), including:

  • Narcotics (pain relievers).
  • Phenobarbital.
  • Sedatives (medicines that cause drowsiness and slow your child’s actions).
  • Procainamide.
  • Antipsychotics (medicines used to treat mental disorders).


Keep metoclopramide (both liquid and tablet) at room temperature in a cool, dry place, away from sunlight. Do not store it in the bathroom or kitchen.

Do not share medicines with others and do not take someone else’s medicine.

Do not keep any medicine that is expired. Talk to your pharmacist about the best way to dispose of leftover or outdated medications.

Keep a list of all the medicines your child uses and show the list to the doctor or pharmacist.

Disclaimer: The article summarizes metoclopramide and does not contain all possible information about this drug.

Not all side effects are listed. If you have questions or want more information about metoclopramide, speak with your healthcare provider.