Enterol: Properties, Pharmacological Effect, Pharmacokinetics, Instructions for Use, Side Effects and Contraindications

It is an antidiarrheal drug that regulates the balance of the intestinal microflora.

Pharmacological properties of enterol

The drug belongs to the group of probiotics (it means to normalize the composition of the intestinal microflora).

According to the instructions, enterol is based on the yeast Saccharomyces boulardii. They come in the intestine to compete for a place on the walls of the intestine with pathogenic and opportunistic microorganisms.

This is due to the antagonistic and antimicrobial effect of enterol against Clostridia, Candida, Klebsiella, Yersinia, Shigella, Staphylococcus and other pathogenic microbes.

Probiotics can also neutralize toxins in the gut – the body’s own toxins and the resulting life of bacteria. Increases the enzymatic activity of the intestine.

When enterol is used inside, it does not change as a result of passage through the digestive tract, but instead colonizes the intestines, which arise 2-5 days after discontinuation.

Pharmacological effect

Enterol is an antidiarrheal medicine. The action of enterol is caused by an antagonistic effect against pathogenic and opportunistic microorganisms:

  • Clostridium difficile.
  • Klebsiella pneumonia.
  • Staphylococcus aureus.
  • Pseudomonas aeruginosa.
  • Candida kruesei.
  • Candida albicans.
  • Pseudotropicalis.
  • Candida.
  • Salmonella typhimurium.
  • Escherichia coli.
  • Shigella dysenteriae.
  • Yersinia enterocolitica.
  • Entamoeba histolytica.
  • Lamblia intestinalis.

It has an antitoxic effect , especially against bacterial cytotoxies and enterotoxins. Improves the enzymatic function of the intestine. Saccharomyces boulardii has a natural resistance to antibiotics.

Pharmacokinetics

After taking the drug it passes through the digestive tract in unchanged form without colonization. The drug is completely eliminated from the body within 2 to 5 days after discontinuation.

Instructions for use of enterol

The drug is intended for oral administration. The capsules are swallowed whole with water. If enterol is indicated in young children, and you have difficulty swallowing, the capsule can be opened, or to use the medicine in bags, and add it to the drink.

For a better effect of the treatment, you should refrain from taking the drug immediately after a meal, to withstand the range of 1-2 hours.

Since the base of probiotics contains living cells, it should not be added to food or drunk at 50 degrees hot, or mixed with alcohol. Do not use enterol as the only means of treating diarrhea, fluid replacement to the outside is required in any way possible, orally or parenterally.

Enterol is approved for use in children in the neonatal period. Dosage up to 1 year – 1 capsule (pack) per day, from 1 to 3 years – 1 capsule (sachet), 2 times a day, over 3 years 2 1-2 capsules twice a day. The course depends on the severity of your bowel symptoms and is determined by your doctor.

Do not use this probiotic simultaneously with antifungal medications.

Dosage

Adults and children over 3 years: 1-2 capsules 2 times / day for 7-10 days.

Children 1-3 years – the drug is prescribed for 1 capsule 2 times / day for 5 days.

The capsules should be taken 1 hour before meals and washed with a small amount of liquid. For young children, and also in case of difficulty in swallowing, the capsule can be opened and its contents given with cold or slightly lukewarm water.

It is not recommended to drink and dilute the drug with hot water and alcoholic beverages.

Admission of the drug for the treatment of acute diarrhea must necessarily be accompanied by rehydration.

Side effects

  • Sickness.
  • Vomiting
  • Dizziness
  • Drowsiness.
  • Headache.
  • Discomfort.
  • Acne.
  • Fever.
  • Joint pain
  • Brown urine
  • Anemia.

Contraindications

  • The presence of a central venous catheter: rare cases of fungemia in patients with a central venous catheter in hospital conditions are described.
  • Hypersensitivity to the components of the drug.

Pregnancy and breastfeeding

The indication of enterol during pregnancy and during lactation is justified only if the expected benefit to the mother exceeds the potential risk to the fetus or baby.

Special instructions

The patient should be informed that if there is no improvement in the 2 days, as well as an increase in body temperature, the detection of mucus or blood in the stool should consult a doctor.

The sensation of thirst and dryness in the mouth indicates insufficient rehydration of the patient.

Overdose

Currently, cases of an enterol overdose are not described.

Interaction

The simultaneous application of enterol and antifungal drugs decreases the clinical effectiveness of enterol (this combination is not recommended).

Pharmacy Release Terms

The drug is approved for use as an over-the-counter medium.

Terms and conditions of storage

The drug should be stored out of the reach of children at a temperature of 15 ° to 25 ° C. The shelf life is 3 years.