Cloxacillin: What is it? Administration, Side Effects, Precautions and Storage

It is a medication found within the family of antibiotics and is used to cure, treat and stop a wide range of bacterial infections.

Cloxacillin is a type of penicillin and does not work to cure diseases linked to viral infections, such as the flu or common cold, so it can not be taken to treat those types of conditions because otherwise, it will not work.


This medicine must be ingested according to the dose recommended by the treating doctor and for the time that he considers to be fully effective. It is recommended to take it on an empty stomach for better absorption; it could be between an hour before or two hours after meals.

The amount to ingest will depend on the condition and the seriousness of the affected state. When used to treat children, it is suggested that before indicating the treatment, the child’s age is weighed and taken into account for the period and the amount of medication to be prescribed.

Because it is an antibiotic, the treatment should be taken at the indicated times and without losing or forgetting a dose. The bacteria can become immune, or Cloxacillin loses effectiveness or takes longer to kill the infection.

Under no circumstances should the patient stop treatment without telling his treating doctor even if he feels improvements because he may relapse after a short time.

Side effects

Antibiotics rarely have large-scale adverse effects on the patient’s health. However, it can cause:


  • Diarrhea or upset stomach
  • Stomach gases.
  • Nausea or vomiting
  • Sores in or around the mouth.

Suppose the affected person has such symptoms for a prolonged period. In that case, they should contact their treating physician to perform some studies and determine if it is necessary to change the dosage or the complete treatment.

In some cases, the black or hairy tongue can develop; it is rare and usually disappears after the treatment; the important thing is to maintain excellent oral hygiene and brush the tongue constantly.

Cloxacillin can produce a low percentage of severe conditions for the organism, and before that, the following symptoms appear:

  • Muscle pain.
  • Chronic and unusual tiredness.
  • Pain in the throat persistently and without signs of improvement.
  • Inflammation in the joints.
  • The easy appearance of hemorrhages.
  • Dark urine or bad smell.
  • Renal problems.
  • Yellowish skin or eyes
  • Abdominal pain.
  • Bleeding without previous injuries.

If the patient has several of the symptoms indicated above, it is recommended that you stop using Cloxacillin or contact your treating doctor immediately.

It is not usual for Cloxacillin to cause severe intestinal conditions associated with Clostridium difficile, which is a bacteria resistant to Cloxacillin components, so the use of antidiarrheals is not recommended if the patient presents the following symptoms:

  • Abdominal pain or spasms.
  • Mucus in the stool.
  • Bleeding when defecating
  • Chronic or persistent diarrhea.

This medication can not be used for prolonged periods; if the condition is not eliminated with the treatment indicated by the specialist doctor, the dosage or drug should be changed because Cloxacillin can cause a vaginal infection in women due to fungi or thrush. oral

That is why the patient should pay close attention if he has the following symptoms:

  • Itching on the lips
  • White spots in the mouth.
  • In the case of women, change in the color and odor of the vaginal discharge.
  • Discomfort, pain, or burning when urinating.
  • Difficulty in enduring the urge to urinate.

Some people may have an allergic reaction but usually do not present significant complications for the affected person. The symptoms are:

  • Inflammation in the face.
  • Rash on the extremities of the body.
  • Redness on the cheekbones of the beginning.
  • Acne.
  • Itching in the skin

Precautions or considerations to evaluate

Cloxacillin can affect the functioning of vaccines, as is the case of the vaccine destined to prevent typhoid fever, which is why vaccines are usually not administered. At the same time, the patient is being treated with Cloxacillin.

This medication is expelled in the urine; if the patient has any condition in that area, it is not recommended that you use this drug unless it is strictly necessary and under medical supervision.


Cloxacillin should be stored in spaces away from sunlight and humidity at an ambient temperature. It should not be refrigerated, and its storage should be out of the reach of children or pets to prevent unsupervised intake as it can generate harmful effects on your health.