Ciproflox: Uses, Presentations, Administration, Side Effects, Precautions, Interactions and Storage

It is an antibiotic that belongs to the family of medicines known as quinolones .


It is used to treat a variety of infections caused by certain bacteria. It does not work for virus infections (like the common cold).

It is most often used to treat infections of the skin, sinuses, bones, lungs, abdomen, kidneys, prostate, and bladder.

It can also be used to treat some sexually transmitted infections (STIs), some forms of infectious diarrhea, and typhoid fever .


Tableta de Ciproflox de 250mg

Each round, white, film-coated and biconvex tablet, identified with “APO” on one side and “CIP” on “250” on the other, contains Ciprofloxa HCl monohydrate equivalent to 250mg of Ciprofloxa.

Ciproflox tablet of 500mg

Each biconvex, capsule-shaped, white, film-coated tablet, engraved “APO-500” on one side, contains Ciprofloxa HCl monohydrate equivalent to 500 mg of Ciprofloxa.

Tableta de Ciproflox de 750mg

Each biconvex, capsule-shaped, white, film-coated tablet, engraved “APO-750” on one side, contains Ciprofloxa HCl monohydrate equivalent to 750mg of Ciprofloxa.

Non-medicinal ingredients in the 250mg, 500mg and 750mg tablets : colloidal silicon dioxide, croscarmellose sodium, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol and titanium dioxide.


The recommended dose for adults of Ciprofloxa tablets varies from 250mg to 750mg twice a day. Depending on the type of infection being treated, you may need to take Ciprofloxa for 3 to 14 days.

For bone infections, it may be necessary to take Ciprofloxa for up to 3 months. For sexually transmitted infections, the dose is administered once as a single dose.

Ciprofloxa tablets can be taken with food or on an empty stomach. Drink plenty of fluids while taking Ciprofloxa and avoid dairy products.

Although Ciprofloxa can be taken with foods that include milk, take this medication at least 2 hours before or 6 hours after taking other products that can join it, decreasing its effectiveness. Ask your pharmacist about the other products you take.

Some examples include: quinapril, sevelamer, sucralfate, vitamins / minerals (including iron and zinc supplements), and products that contain magnesium, aluminum, or calcium (such as antacids, didanosine solution, and calcium supplements).

Foods rich in calcium, including dairy products (such as milk, yogurt) or calcium-enriched juice, may also decrease the effect of this medication.

Take this medication at least 2 hours before or 6 hours after eating calcium-rich foods, unless you eat these foods as part of a larger meal that contains other foods (not rich in calcium). These other foods decrease the effect of calcium binding.

Ask your doctor or pharmacist about the safe use of supplements / nutritional replacements with this medication.

It is important that you take this medication exactly as prescribed by your doctor. Even if you start to feel better after the start of treatment, it is important to finish the total amount prescribed.

This helps prevent the infection from coming back and is harder to treat. Store the tablets at room temperature and keep them out of the reach of children.

Store the oral suspension at room temperature or in the refrigerator in an upright position, protect it from freezing and keep it out of the reach of children. After 14 days, safely discard any remaining medication.

Side effects

May cause nausea, diarrhea, dizziness, lightheadedness, headache or trouble sleeping.

Tell your doctor right away if you have any serious side effects, including unusual bruising / bleeding, signs of a new infection (such as new / persistent fever, persistent sore throat).

Signs of kidney problems (such as a change in the amount of urine, red / pink urine), signs of liver problems (such as unusual tiredness, stomach / abdominal pain, persistent nausea / vomiting, yellow eyes / skin, dark urine).

However, seek medical attention immediately if you notice any of the following symptoms of a severe allergic reaction: rash, itching / swelling (especially of the face / tongue / throat), severe dizziness, trouble breathing.

Do not use it later for another infection unless your doctor tells you to. Check with your doctor for more details.

Laboratory and / or medical tests (such as kidney function, blood counts , cultures) should be done periodically to monitor their progress or detect side effects.

Do not change brands of this medication without consulting your doctor or pharmacist. Not all brands have the same effects.


Before taking Ciproflox, tell your doctor or pharmacist if you are allergic to it or to other quinolonic antibiotics such as norfloxacin , gemifloxacin, levofloxacin , moxifloxacin or ofloxacin , or if you have any other allergies.

This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Before using this medication, tell your doctor or pharmacist your medical history, especially: diabetes, heart problems (such as recent heart attack ), joint / tendon problems (such as tendinitis, bursitis ), kidney disease .

Liver disease, mental / mood disorder (such as depression ), myasthenia gravis, nerve problems (such as peripheral neuropathy), seizures, conditions that increase the risk of seizures (such as brain / brain injury, brain tumors, cerebral atherosclerosis ).

In rare cases, this medication can cause serious changes in your blood sugar level, especially if you have diabetes. Ciproflox may increase the blood sugar lowering effects of the drug glyburide.

This medicine contains sucrose and, therefore, it is not recommended if you suffer from a rare hereditary metabolic condition (such as fructose intolerance, sucrase-isomaltase deficiency, glucose-galactose malabsorption).

Older adults may be more sensitive to the side effects of this medication, especially tendon problems (especially if they are also taking corticosteroids such as prednisoneor hydrocortisone ) and QT prolongation.


Some products that may interact with this medicine include: “anticoagulants” (such as acenocoumarol, warfarin ). This medicine may increase and / or prolong the effects of caffeine.

Avoid drinking large amounts of caffeinated beverages (coffee, tea, soda), eating large amounts of chocolate, or taking over-the-counter products that contain caffeine.


Before mixing, store the dry powder and the solution of the mixture in an upright position at room temperature. Do not freeze. Discard any unused medication after completing the treatment.

Once mixed, the suspension can be stored upright in the refrigerator or at room temperature. Discard any suspension not used 14 days after mixing. Do not freeze.