Bacillus Coagulans: Presentation, Indications, Mechanism of Action, Dosage, Side Effects, Warnings and Interactions

It is used in a similar way to lactobacilli and other probiotics referred to as “good” bacteria.

Bacillus coagulans is a type of bacteria that produces lactic acid , and is capable of generating spores during its reproductive life cycle, unlike lactobacillus and many other probiotics .

This ability allows B. coagulans to go dormant in harsh conditions, which could kill other probiotics.

For this reason, this strain of bacteria is particularly robust. It is able to withstand extreme environments, such as high levels of acid, in the stomach.

The use of dietary supplements containing Bacillus coagulans is said to aid in the treatment of many health conditions, including various digestive disorders.

Bacillus coagulans, in addition to being used for general digestion problems, is used in the prevention of respiratory infections, and to improve the immune system, as well as for the prevention of cancer .


Its presentation in the market is generally in the form of capsules, it can also be purchased as gel capsules and in vegetarian or vegan formulas. Bacillus coagulans is also available in supplement form.


In alternative medicine, Bacillus coagulans is used to treat the following health problems:

  • Diarrhea , including viral diarrhea in children, traveler’s diarrhea, and diarrhea caused by antibiotics.
  • Digestion problems
  • Irritable bowel syndrome.
  • Inflammatory bowel disease ( Crohn’s disease , ulcerative colitis ).
  • Colitis por Clostridium difficiles.
  • Fighting the growth of unwanted bacteria.
  • Helicobacter pylori infection, which causes stomach ulcers.
  • Respiratory infections.
  • Cancer prevention.
  • Strengthening the immune system.
  • As an added agent to vaccines to improve their effectiveness.

Bacillus coagulans is also said to boost the immune system. Even some proponents of alternative medicine claim that it can also fight cancer.

Additionally, taking Bacillus coagulans while taking antibiotics is thought to help protect against side effects associated with antibiotic use (such as stomach problems and yeast infections).

Mechanism of action of Bacillus Coagulans

There is now evidence that Bacillus coagulans may offer some health benefits.

In the research that is available on Bacillus coagulans, benefits have been reported in the therapy of the following diseases:

Irritable bowel syndrome

Bacillus coagulans contributes to the therapy of some symptoms of irritable bowel syndrome. These symptoms include abdominal pain, bloating, diarrhea, or constipation.

Immune system

Bacillus coagulans helps to stimulate the immune system, which is why it is used to prevent respiratory tract infections that are caused by viruses such as the common cold and flu.

Bacillus coagulans specifically increases the production of cells that are involved in the body’s immune response.

Rheumautoid arthritis

Bacillus coagulans is a probiotic that has valuable benefits in rheumatoid arthritis : less disability, an improved ability to participate in daily activities, such as long walks, it also shows a reduction in C-reactive protein, (a marker for inflammation).

Constipation and intestinal gas

Bacillus coagulans in patients with constipation, show better bowel function and eliminates flatulence, stomach bloating and abdominal pain.

Respiratory tract infection

Bacillus coagulans in the immune system increases the production of T cells.

There is not enough information to know how Bacillus coagulans might work for medical purposes.

But research in animals has reported that bacillus coagulans could increase the activity of the immune system, reducing pathogenic bacteria.


Bacillus coagulans is manufactured by many companies. Some strains of B. coagulans are also owned by specific manufacturers. Since B. coagulans is manufactured by so many companies, there is no set specific dosage for its use.

Probiotics can be administered according to the number of living organisms they contain, often numbering in the billions. They can also be dosed as colony forming units.

The dose is generally 1 to 3 capsules a day, and depends on factors such as the age and health conditions of the patient.

Bacillus Coagulans side effects

Currently, there are no reported side effects when taken as directed. However probiotics of all kinds can trigger allergic reactions.

Warnings and Contraindications

Pregnant and lactating women are advised to avoid taking the supplement, as not enough research has been done on its effects on the fetus or baby.

Bacillus Coagulans interactions

Interaction of antibiotics with Bacillus coagulans

Antibiotics are used to reduce harmful bacteria in the body. Antibiotics can also reduce other bacteria in the body. Taking antibiotics along with Bacillus coagulans could reduce the potential benefits of this drug.

Interaction of immunosuppressants with Bacillus coagulans

Bacillus coagulans might boost the immune system. Taking Bacillus coagulans along with medications that lower the immune system can decrease the effectiveness of the medications.