Bacillus Coagulans: Presentation, Indications, Mechanism of Action, Dosage, Side Effects, Warnings and Interactions

It is used similarly to lactobacilli and other probiotics referred to as “good” bacteria.

Bacillus coagulans are bacteria that produce lactic acid and can generate spores during their reproductive life cycle, unlike lactobacillus and many other probiotics.

This ability allows B. coagulans to go dormant in harsh conditions, which could kill other probiotics.

For this reason, this strain of bacteria is particularly robust. It can withstand extreme environments, such as high acid levels, in the stomach.

The use of dietary supplements containing Bacillus coagulans is said to aid in treating many health conditions, including various digestive disorders.

Bacillus coagulans, in addition to being used for general digestion problems, are used in the prevention of respiratory infections and improve the immune system, as well as for the prevention of cancer.


Its presentation in the market is generally in capsules; it can also be purchased as gel capsules and in vegetarian or vegan formulas. Bacillus coagulants are also available in supplement form.



In alternative medicine, Bacillus coagulans is used to treat the following health problems:

  • Diarrhea, including viral diarrhea in children, traveler’s diarrhea, and diarrhea caused by antibiotics.
  • Digestion problems
  • Irritable bowel syndrome.
  • Inflammatory bowel disease ( Crohn’s diseaseulcerative colitis ).
  • Colitis or Clostridium difficiles.
  • Fighting the growth of unwanted bacteria.
  • Helicobacter pylori infection causes stomach ulcers.
  • Respiratory infections.
  • Cancer prevention.
  • Strengthening the immune system.
  • As an added agent to vaccines to improve their effectiveness.

Bacillus coagulans are also said to boost the immune system—even some proponents of alternative medicine claim that it can also fight cancer.

Additionally, taking Bacillus coagulans while taking antibiotics is thought to help protect against side effects associated with antibiotic use (such as stomach problems and yeast infections).

Mechanism of action of Bacillus Coagulans

There is now evidence that Bacillus coagulans may offer some health benefits.

In the research that is available on Bacillus coagulans, benefits have been reported in the therapy of the following diseases:

Irritable bowel syndrome

Bacillus coagulans contribute to the therapy of some symptoms of irritable bowel syndrome. These symptoms include abdominal pain, bloating, diarrhea, or constipation.

Immune system

Bacillus coagulans help stimulate the immune system, which is why it is used to prevent respiratory tract infections caused by viruses such as the common cold and flu.

Bacillus coagulans explicitly increase the production of cells involved in the body’s immune response.

Rheumautoid arthritis

Bacillus coagulans is a probiotic that has valuable benefits in rheumatoid arthritis: less disability and an improved ability to participate in daily activities, such as long walks; it also reduces C-reactive protein (a marker for inflammation).

Constipation and intestinal gas

Bacillus coagulans in patients with constipation show better bowel function and eliminate flatulence, stomach bloating, and abdominal pain.

Respiratory tract infection

Bacillus coagulant in the immune system increases the production of T cells.

There is not enough information to know how Bacillus coagulans might work for medical purposes.

But research in animals has reported that Bacillus coagulans could increase the activity of the immune system, reducing pathogenic bacteria.


Bacillus coagulans are manufactured by many companies. Some strains of B. coagulans are also owned by specific manufacturers. Since B. coagulans is manufactured by so many companies, there is no set particular dosage for its use.

Probiotics can be administered according to the number of living organisms they contain, often numbering in the billions. They can also be dosed as colony-forming units.

The dose is generally 1 to 3 capsules a day and depends on factors such as the age and health conditions of the patient.

Bacillus Coagulans side effects

Currently, there are no reported side effects when taken as directed. However, probiotics of all kinds can trigger allergic reactions.

Warnings and Contraindications

Pregnant and lactating women are advised to avoid taking the supplement, as not enough research has been done on its effects on the fetus or baby.

Bacillus Coagulans interactions

Interaction of antibiotics with Bacillus coagulans

Antibiotics are used to reduce harmful bacteria in the body. Antibiotics can also reduce other bacteria in the body. Taking antibiotics along with Bacillus coagulans could reduce the potential benefits of this drug.

Interaction of immunosuppressants with Bacillus coagulans

Bacillus coagulans might boost the immune system. Taking Bacillus coagulans and medications that lower the immune system can decrease the effectiveness of the medicines.