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It is a medicine that counteracts (neutralizes) the acid in the stomach to relieve indigestion and heartburn.
They come in liquid or chewable tablets and can be purchased in pharmacies and stores without a prescription.
Indications
Almax can be helpful if you have:
Indigestion, heartburn or acid reflux – also known as gastroesophageal reflux disease, a stomach ulcer, gastritis (inflammation of the stomach lining).
They can relieve your symptoms quickly for a few hours. But they do not treat the underlying cause, and long-term use is not recommended. Talk to your GP if you notice that you need to take Almax regularly.
Almax Administration
Check the directions on the package or insert to see how much Almax to take and how often. Almax should be used when you have symptoms or think you will have them soon.
For most people, the best time to take it is with or shortly after meals, and just before bedtime. Remember that Almax doses for children should be lower than for adults.
Contact your GP or pharmacist if you take too much medicine and start to feel unwell.
Take Almax with food, alcohol, and other medications
It is best to take Almax with food or shortly after eating, as this is when you are most likely to have indigestion or heartburn. The effect of the medicine may also last longer if it is taken with food.
Almax can affect how other medicines work, so you should not take other medicines within two to four hours.
You can drink alcohol while taking Almax, but alcohol can irritate your stomach and make your symptoms worse.
Side effects
Almax generally does not have many side effects if it is only taken occasionally and at the recommended dosage. But sometimes it can cause:
Diarrhea or constipation, flatulence (gas), stomach cramps, and feeling sick or vomiting. These should pass once you stop taking the medicine.
Talk to a pharmacist or your GP if they do not improve or are bothersome. You may need to change to another drug.
Contraindications of Almax
Almax is safe for most people, although they are not suitable for everyone. Check with a pharmacist or your GP first if:
You are pregnant or breastfeeding: Most antacid medications (such as Almax) are considered safe to take during pregnancy or breastfeeding, but always get advice first.
You are looking for a medicine (such as Almax) for a child under 12 years of age – some antacids are not recommended for children.
You have liver disease, kidney failure, or heart failure – Almax may not be safe if you have one of these problems.
You have a disease that means you need to control the amount of salt (sodium) in your diet: such as high blood pressure or cirrhosis (liver scarring), Almax contains high levels of sodium, which may make you feel unwell.
Are taking other medications: Almax can interfere with other medications and may need to be avoided or taken at another time.
Pharmacological studies
Pharmacological screening tests have been performed to provide an initial evaluation of the new antacid compound Almax or almagate (aluminum magnesium hydroxycarbonate hydrate, Al2Mg6 (OH) 14 (CO3) 2 X 4 H2O, Almax).
In rats with pyloric ligatures, Almax (125-500 mg / kg) was significantly more potent than aluminum hydroxide in raising the pH and reducing the total acidity of the gastric juice produced, without affecting the secreted volume.
Pepsin activity in gastric juice was also significantly inhibited by Almax even after adjustment to the optimal enzyme pH 2, a phenomenon not demonstrable with aluminum hydroxide.
Almax at oral doses up to 3 g / kg had no effects on the central, autonomic and somatic nervous systems in mice, nor at 500 mg / kg did it influence the cardiovascular system or blood pressure responses to agonist drugs in cats anesthetized.
The results confirm that Almax is a potent antacid without systemic pharmacological or toxicological effects.
Clinical trial
An open multicenter trial of a new clinical antacid, almagate (hydrated aluminum magnesium hydroxycarbonate, Al2Mg6 (OH) 14 (CO3) 2 X 4 H2O, Almax) has been performed in 169 patients with gastric heartburn (heartburn).
Clinical and endoscopic examination revealed that 104 of the patients had an active duodenal ulcer and 60 of these (group II) were treated with antisecretory drugs (cimetidine or ranitidine) plus Almax and 44 (group III) with Almax alone.
Endoscopic examination in the remaining 65 patients (group I) did not reveal the presence of an ulcer and they were also treated with Almax alone. In all groups, Almax was shown to be very effective and the majority of patients had no symptoms at the end of the two-week trial.
79.5% of the patients with ulcers in group III required doses of 6-8 g / d, while only 21.7% of those in group II with concomitant treatment with antisecretory drugs took more than 4 g / d.
Group I non-ulcer patients also used lower doses and only 29.3% needed to reach 6-8 g / d. There was a significant increase in daily bowel movements in all groups, which most patients found advantageous.
The general tolerance was excellent and the side effects (diarrhea 7 cases, nausea 5 cases and constipation 1 case) were few and transitory and 84.2% of the patients expressed a clear preference for Almax over their previous antacid treatment.
Frequently asked questions about Almax
What is the start of action?
The maximum effect of this medicine can be seen in 1 to 2 hours for an immediate-release tablet, 1.5 to 2 hours for a disintegrating tablet, and 9 hours for an extended-release tablet.
What is the duration of the effect?
The effect of this drug lasts an average duration of 44 hours for an immediate release tablet and 52 hours for an extended release tablet / disintegrating tablet.
Is it safe with alcohol?
Alcohol consumption with this medicine is not recommended as it increases the risk of severe respiratory depression and dyspnea.
Do you create a habit?
The tendency to habit formation has been reported.
Use in pregnancy?
The use of this medicine in pregnant women is not recommended unless absolutely necessary and only under the supervision of the doctor.
Use during lactation?
This drug is known to be excreted in human breast milk and may cause unwanted effects in breastfed babies. Therefore, it is not recommended for use in breastfeeding women.
