Advantan: Uses, Dosage, Side Effects, Contraindications and Warnings

Its rapid efficacy and the lack of undesirable local and systemic side effects make it especially suitable for use in children and infants.

Methylprednisolone Acetate (MPA) has provided a fast, reliable, and highly effective treatment for eczematous disorders, with efficacy comparable to most reference topical corticosteroids.

It also has excellent local and systemic tolerability. MPA is effective in treating facial and scalp eczema and sunburn and has shown promising results in the treatment of psoriasis.

The wide range of formulations (0.1%) of MPA, including cream, ointment, ointment, milk, and solution, allow the treatment to be adapted to the individual patient.

In addition, MPA has the advantage of once-a-day application compared to twice-daily treatment for other topical corticosteroids, which improves patient safety and promotes patient compliance, but without compromising efficacy.

It is a prescription drug applied topically, directly to the skin, and is not intended to be taken orally. It is also prescribed to treat skin conditions such as inflammation, allergic reactions, and eczema. It can also help with itching, burning, and shallow pain.

When applying Advantan, use only a thin layer. Using too much can exacerbate possible side effects.



Avant is often used in the treatment of:

  • Autoimmune diseases.
  • Hematological diseases.
  • Hypersensitivity
  • Inflammation.
  • Neoplasms.
  • Neurological manifestations.

It is also used in the prevention of:

  • Graft versus host disease.

This medicine may be prescribed for other uses. Consult your doctor or pharmacist for more information.

Other drugs whose main active compound is Metilprednisolone Acetate can be found under the following names:

  • A-MethaPred.
  • Depo-Medrol.
  • HybriSil.
  • Medrol.
  • Solu-Medrol.

Methylprednisolone acetate is part of the class of drugs:

  • Corticosteroids, powerful group III.


Use Methylprednisolone Accepatide precisely as directed by your doctor. Follow the instructions carefully on your prescription label.

The dose your doctor recommends will be based on the following (use any or all that apply):

  • The condition that is being treated.
  • Other medical conditions you have.
  • Other medications you are taking.
  • How you respond to this medication
  • Your weight
  • Your height.
  • Your age.
  • Your gender

Most common side effects

You may experience an allergic reaction to Advantan. Never use this product if you are allergic to the components.

You may experience side effects like skin discoloration, folliculitis, perioral dermatitis, hypertrichosis, and skin atrophy. You may also notice dryness of the skin.

According to medical studies, these side effects can worsen if you apply Advantan to a large part of your body (around 10% or more). Talk to your doctor about the risks of this product getting absorbed into your body. Systemic absorption can lead to the suppression of the function of your adrenal glands.


This medication should not be applied to areas of the skin infected with acne. It should also not be used in cases of many viral infections, such as herpes zoster, or by patients with tuberculosis or syphilis. Do not apply Advantan to any area where your skin reacts to a vaccination.

Talk to your doctor about other possible contraindications when disclosing all of your pre-existing medical conditions.


Unless your doctor tells you otherwise, never use Advantan on your face, especially around the eyes. According to the professional opinion, glaucoma may develop if this medication is used near the eyes for a prolonged period.

Using Advantan on the face can also make redness worse on the skin.

Pregnancy:  Pregnant women should consult their doctor carefully before considering a topical medication such as Advantan. Many pharmaceutical experts warn that it should never be used during pregnancy or breastfeeding.

You may run the risk of your baby developing congenital disabilities.

Time frame

Even if only applied topically, some medications should not be used for a prolonged period; the Advantan is no exception.

Adults should use Advantan for no longer than 12 weeks. Children who use Advantan should stop using it at four weeks. The application of Advantan for this period can cause skin problems, such as loss of elasticity and thinning of the skin.

It can also cause dilation of blood vessels and ecchymosis, and telangiectasia.