Propylamine: What is it? Uses, Chemical Properties, Contact Hazards, Prevention and Toxicity

It is known as a regulatory agent for plastics.


It works as an intermediate for pharmaceuticals, coating materials, pesticides, rubber chemicals, fiber, textiles and other organic products . It is also commonly used as an additive in the oil industry.

Regarding its physical state, characteristics and appearance, it can be said that it is liquid, colorless and hygroscopic, with a characteristic odor.

What are its chemical properties?

Acidity 10.53
Appearance Hygroscopic colorless liquid
Boiling point 48ºC
CAS number 107-10-8
Density 0.719gcm  3
Hs code 2921.19
IUPAC name Propan-1-amine
Melting point -83ºC
Molar mass 59.11g / mol
molecular formula 3 H 9 N
NFPA 704 H-3, F-3, R-0, C-NA
Solubility Miscible
Synonyms Propelamine (8CI); 1-aminopropane; 1-propylamine; Mono-n-propylamine; NSC7490; Propan-1-ylamine; n-Propylamine

Possible hazards in contact with propylamine

Possible physical hazards: since vapor is heavier than air, then it can travel along the ground; distant ignition also possible.

Possible Chemical Hazards: Propylamine tends to decompose on burning, producing a certain amount of fumes that become toxic to humans ( nitrogen oxides ).

This compound is a moderately strong base, which is capable of reacting with acids and is corrosive to aluminum and zinc. It responds extremely violently to contact with oxidants and mercury, causing a fire hazard and even the possibility of explosion.

It is also known to react very dangerously to a great variety of compounds such as halogenated hydrocarbons, alcohols and even some nitroparaffins. It can even attack copper and copper alloys.

Regarding the exhibition

Routes of exposure: the substance can be absorbed into the body by inhalation of its vapor and even by ingestion.

Inhalation Hazard: Harmful air pollution can be reached fairly quickly due to evaporation of this substance at 20 ° C.

Some short-term exposure effects: Propylamine is highly corrosive to the eyes, the skin, and even the respiratory tract.

Types of danger and prevention





FIRE Highly flammable. Gives off irritating or toxic gases (or gases) in a fire. There are NO open flames, NO sparks and NO smoking. Alcohol-resistant powder or foam, large amounts of water, and carbon dioxide.


Vapor or air mixtures are highly explosive.

Closed system, ventilation, explosion-proof electrical equipment and lighting. DO NOT use compressed air to fill, discharge, or handle. In case of fire: keep drums, etc., cool by spraying them with water.
•Inhalación Burning sensation, Cough. Labored breathing, shortness of breath and throat odor. Ventilation, local exhaust, or immediate respiratory protection is recommended. Fresh air, rest

Redness of the skin and a feeling that it burns. Symptoms of pain and blisters are usually present


Protective gloves. Protective clothes

Remove contaminated clothing. Rinse skin with plenty of water or shower. Seek medical attention
•Ojos Redness. Pain. Loss of vision Severe deep burns. Face shield or eye protection in combination with respiratory protection. First rinse with plenty of water for several minutes (remove contact lenses if possible), then see a doctor.
•Ingestión Abdominal pain. Burning sensation. Headache. Shock or collapse. You should never eat, drink or smoke while working with the compound. Rinse mouth, do not induce vomiting. Drink lots of water. Remember to seek medical attention.

Regarding the product treaty

Spill removal

The danger area should be evacuated and an expert should always be consulted. You must remove and eliminate all sources of ignition.

It is important to collect the leaking liquid in sealable containers. Spilled liquid also needs to be washed off with large amounts of water. As additional personal protection, the use of chemical protective suit including self-contained breathing apparatus is recommended.


Storage must be non-combustible. It should be separated from strong oxidants, acids, food. Likewise, it is important to remember that it must always be kept tightly closed.

Packaging and labeling

  • It should never be transported with food.
  • UN Hazard Class: 3.
  • United Nations affiliate risks: 8.
  • United Nations Packing Group: II.


Toxicity range

The range of toxicity varies among the many substances classified as irritants. Toxicity depends on a large number of factors, including concentration, mechanism of action, pH, free acidity and alkalinity, molarity, and oxidation reduction potential.

Mild to moderate toxicity

These types of irritants usually have a level of toxicity that can range from mild to moderate, characterized by swelling, redness and pain anywhere, especially on the mucous membranes.

The mouth, nose, and eyes are commonly affected as well. After inhalation symptoms such as coughing, tachypnea, and wheezing are common.

When ingestion occurs, nausea, vomiting, and diarrhea are expected as predominant symptoms. Direct contact with the skin can cause exposure, redness, swelling, and pain.