Dimethylamine: Definition, Properties, Side Effects, Environmental Uses and Symptoms of Poisoning

Specifically, it is a colorless, liquefied, flammable gas with an ammonia and fish odor.

Dimethylamine (DMA) is a secondary organic amine. It is abundantly present in human urine.

Significant sources of urinary DMA have been reported to include trimethylamine N-oxide, a common dietary component, and asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide (NO) synthesis.

ADMA is excreted in the urine partly unmetabolized and partly after hydrolysis to DMA by dimethylarginine dimethylaminohydrolase (DDAH).

Statistically significant increases in urinary DMA have been found in individuals after consuming fish and shellfish. The highest values ​​were obtained for the people who consumed coley, squid, and blue whiting with cod, haddock, sardine, skate, and swordfish.

In addition, dimethylamine is available in 2 different forms:

  • As anhydrous liquefied gas, 100% DMA.
  • As an aqueous solution, DMA 40 and 60%.

Properties of the substance

  • Appearance: white to off-white crystalline powder.
  • CAS number: 506-59-2.
  • Density: 0.64 g / cm 3.
  • EINECS number: 208-046-5.
  • HS code: 29211190.
  • IUPAC Name: N-Methylmethanamine Hydrochloride.
  • InChI: 1S / C2H7N.ClH / c1-3-2; / h3H, 1-2H3; 1H.
  • Main hazards: harmful.
  • Melting point:  170-173 ° C.
  • Molar mass : 81.54 g / mol.
  • NFPA 704: H-3, F-4, R-0, C-NA.
  • RTECS number: IQ0220000.
  • Solubility: 3000 g / l.
  • Boiling point: 7.0 ° C.
  • Relative density (water = 1): 0.7.
  • Solubility in water: 354 g / 100ml.
  • Vapor pressure, kPa at 25 ° C: 203.
  • Flash point: flammable gas.
  • Auto-ignition temperature: 400 ° C.
  • Explosive limits, vol% in air: 2.8-14.4.
  • Octanol / water partition coefficient as log Pow: -0.2.

Side effects caused by dimethylamine

The following is a list of possible side effects from medications containing dimethylamine or from direct contact with the substance. This is not an understandable list; the side effects presented are, in many cases, highly probable, although they do not always occur.


Specific side effects can be more bizarre, profound, or essential. You should consult with your trusted doctor if you notice any side effects listed below, especially if they do not go away. This has been reported:

  • It generates a large amount of sneezing.
  • Irritation in any part of the skin.
  • Tos.
  • Dyspnoea or shortness of breath.
  • Pulmonary edema.
  • Conjunctivitis.
  • Dermatitis.

Dimethylamine can also cause specific side effects not mentioned here, as they will also depend on each person.

Uses of dimethylamine in the environment

In its purest form, dimethylamine can be used as a depilatory agent in tanning, for various dyes, during rubber accelerators, in many soaps, for creating cleaning compounds, and as an agricultural fungicide which is its best-known use.

DMA can also be nitrosated under weak acid conditions to give dimethylnitrosamine to the body. In addition, dimethylamine is used as a raw material for dimethylformamide, dimethylacetamide, dimethylaminoethyl ethanol, surfactants, and pesticides. In addition, it is commonly used to treat water.

It is also used for the following applications or uses:

  • Chemical and petrochemical products.
  • In the production of asphalt.
  • Fungicides int.
  • Herbicides – intermediate for 2,4-d.
  • Herbicides – medium for glyphosate.
  • Domestic and industrial intermediate care.
  • Intermediate.
  • Specialty chemicals.
  • For the maintenance of hard surfaces.
  • During domestic and industrial intermediary maintenance.
  • For paints and coatings.
  • In photographic chemicals.
  • During the rubber modification.
  • In the industrial water treaty.

Signs and Symptoms of Dimethylamine Poisoning

Exposure route Symptoms First aid

Inhalation Burning sensation. Cough. Headache. They strained breathing, Shortness of breath Sore throat. Symptoms can be delayed—fresh air rest Half upright position. Artificial respiration may be required. Seek medical attention.

Skin In contact with liquid: freezing In case of frostbite, rinse with plenty of water, and do not remove clothing. Seek medical attention.

Eyes Redness. Pain. Blurry vision. First, rinse with plenty of water for several minutes (remove contact lenses if possible) and then take a doctor.

Among other environmental data, the substance is known to be harmful to aquatic organisms, so caution should be exercised.

This substance is easily flammable, harmful by inhalation, and corrosive, in addition to which it can cause burns. It is recommended to keep away from any flame or source of sparks. It is essential not to smoke around the substance.

Suitable clothing, gloves, and eye and face protection should be worn. In case of an accident or if you feel unwell, see a doctor immediately (if possible, show him the signs).