Dimethylamine: Definition, Properties, Side Effects, Environmental Uses and Symptoms of Poisoning

Specifically, it is a colorless, liquefied and flammable gas with an ammonia and fish odor.

Dimethylamine (DMA) is an organic secondary amine . It is abundantly present in human urine.

Major sources of urinary DMA have been reported to include trimethylamine N-oxide, a common dietary component, and asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide (NO) synthesis.

ADMA is excreted in the urine partly unmetabolized and partly after hydrolysis to DMA by imethylaginine dimethylaminohydrolase (DDAH).

Statistically significant increases in urinary DMA have been found in individuals after consumption of fish and shellfish. The highest values ​​were obtained for the people who consumed coley, squid and blue whiting with cod, haddock, sardine, skate and swordfish.

In addition, dimethylamine is available in 2 different forms:

  • As anhydrous liquefied gas, 100% DMA.
  • As an aqueous solution, DMA 40 and 60%.

Properties of the substance

  • Appearance: white to off-white crystalline powder.
  • CAS number: 506-59-2.
  • Density: 0.64 g / cm 3.
  • EINECS number: 208-046-5.
  • HS code: 29211190.
  • IUPAC Name: N-Methylmethanamine Hydrochloride.
  • InChI: 1S / C2H7N.ClH / c1-3-2; / h3H, 1-2H3; 1H.
  • InChIKey: IQDGSYLLQPDQDV-UHFFFAOYSA-N.
  • Main hazards: harmful.
  • Melting point:  170-173 ° C.
  • Molar mass : 81.54 g / mol.
  • NFPA 704: H-3, F-4, R-0, C-NA.
  • RTECS number: IQ0220000.
  • Solubility: 3000 g / l.
  • Boiling point: 7.0 ° C.
  • Relative density (water = 1): 0.7.
  • Solubility in water: 354 g / 100ml.
  • Vapor pressure, kPa at 25 ° C: 203.
  • Flash point: flammable gas.
  • Auto-ignition temperature: 400 ° C.
  • Explosive limits, vol% in air: 2.8-14.4.
  • Octanol / water partition coefficient as log Pow: -0.2.

Side effects caused by dimethylamine

The following is a list of possible side effects that can occur from medications containing dimethylamine or from direct contact with the substance. This is not an understandable list, the side effects presented are in many cases highly probable, although they do not always occur.

Certain side effects can be more bizarre, serious, or very important to deal with. You should consult with your trusted doctor if you notice any of the side effects listed below, especially if they do not go away. This has been reported:

  • It generates a large amount of sneezing.
  • Irritation in any part of the skin.
  • Tos.
  • Dyspnoea or shortness of breath.
  • Pulmonary edema.
  • Conjunctivitis.
  • Dermatitis.

Dimethylamine can also cause certain side effects not mentioned here, as they will also depend on each person.

Uses of dimethylamine in the environment

In its purest form, dimethylamine can be used as a depilatory agent in tanning, for various dyes, during rubber accelerators, in many soaps, for creating cleaning compounds, and as an agricultural fungicide which is its best known use.

In the body, DMA can also be nitrosed under weak acid conditions to give dimethylitrosamine. In addition, dimethylamine is used as a raw material for dimethyl formamide, dimethylacetamide, dimethylaminoethyl ethanol, surfactants, and pesticides. In addition, it is commonly used to treat water.

It is also used for the following applications or uses:

  • Chemical and petrochemical products.
  • In the production of asphalt.
  • Fungicides int.
  • Herbicides – intermediate for 2,4-d.
  • Herbicides – intermediate for glyphosate.
  • Domestic and industrial intermediate care.
  • Intermediate.
  • Specialty chemicals.
  • For the care of hard surfaces.
  • During domestic and industrial intermediary care.
  • For paints and coatings.
  • In photographic chemicals.
  • During the rubber modification.
  • In the industrial water treaty.

Signs and Symptoms of Dimethylamine Poisoning

Exposure route Symptoms First aid
Inhalation Burning sensation. Cough. Headache. Strained breathing Shortness of breath Sore throat. Symptoms can be delayed. Fresh air rest Half upright position. Artificial respiration may be required. Seek medical attention.
Skin In contact with liquid: freezing In case of frostbite, rinse with plenty of water, do not remove clothing. Seek medical attention.
Eyes Redness. Pain. Blurry vision. First rinse with plenty of water for several minutes (remove contact lenses if possible) and then take a doctor.

Among other environmental data, the substance is known to be really harmful to aquatic organisms, so caution should be exercised.

This substance is easily flammable, harmful by inhalation and corrosive, in addition to which it can cause burns. It is recommended to keep away from any flame or source of sparks. It is important not to smoke around the substance.

Suitable clothing, gloves, and eye and face protection should be worn. In case of accident or if you feel unwell, see a doctor immediately (if possible, show him the signs).