Through an exam, it is analyzed to control the possible consequences of having diabetes.
Known as the hemoglobin to which glucose binds. The high level of glycosylated hemoglobin increases in the red blood cells of people with poorly controlled diabetes mellitus .
Since glucose remains bound to hemoglobin during the life of red blood cells (normally around 120 days), the level of glycosylated hemoglobin reflects the average blood glucose level, thus the analysis mentioned on the consequences of suffering from diabetes is carried out.
The normal level for glycosylated hemoglobin is less than 7%. Diabetics rarely reach such levels, but strict control aims to approach the mentioned percentage.
Levels above 9% show poor control and possible conditions, and levels above 12% show poor control in the patient.
It is commonly recommended to measure glycosylated hemoglobin every 3 to 6 months in diabetes.
The Diabetes Control and Complications Trial (DCCT) demonstrated that diabetics who maintain their glycosylated hemoglobin levels close to 7% are much more likely to delay or prevent complications of diabetes that affect the eyes and kidneys.
A change in treatment is almost always needed if the level is above 8%. Decreasing the level of glycosylated hemoglobin in any amount improves a person’s chances of staying healthy.
Glycosylated hemoglobin is also known as glycohemoglobin or as hemoglobin A1C (the major fraction of glycosylated hemoglobin).
Importance of the test
Hemoglobin is the substance within the red blood cells that carries oxygen to the cells of the body.
Glucose molecules (a type of sugar) in the blood normally adhere to the hemoglobin molecules; This means that hemoglobin has been glycosylated, hence the term comes (also known as hemoglobin A1c or HbA1c).
As a person’s blood sugar level increases, a greater amount of the person’s hemoglobin is glycosylated.
Glucose remains bound to hemoglobin during the life of the red blood cell, or approximately 2 to 3 months as previously mentioned.
A blood test can measure the amount of glycosylated hemoglobin in the blood. The glycosylated hemoglobin test shows the average blood glucose level of a person during the 2 to 3 months before the test.
This can help determine how well a person’s diabetes is controlled over time.
Formation of glycosylated hemoglobin
Hemoglobin Glucose or Hemoglobin A1c HbA1c is a lower fraction of adult hemoglobin, which is formed slowly and not enzymatically, ie high levels of energy that would make it much faster.
Because the erythrocytes, which are round blood cells, are freely permeable to glucose.
The glycosylated hemoglobin is formed throughout the life of the erythrocyte; Its rate of formation is directly proportional to the concentration of glucose environment or organic environment.
The concentration of HbA1c or glycosylated, provides a ” glycemic history ” of the previous 120 days, which is the average life expectancy of erythrocytes, the agglomeration of this hemoglobin gives life to the aforementioned cells that are located in the blood.
The tests of blood glucose and ketones (when we talk about ketone in the blood is a reference that the body does not use glucose to provide energy to the body) make the results of a medical examination are nothing positive to the patient.
A urine test provides useful information for the daily management of diabetes, while HbA1c provides important information on recent average glycemic control.
It is an integral component of the treatment of patients with diabetes and is used to control glycemic control in the long term and as a measure of the risk for the development of complications of diabetes.
Patients with a high level of medical results in reference to this hemoglobin must maintain a monitorio of the percentages thrown for the control in time that does not cause actions without medical solutions.
Sometimes not controlling these contributions cause other diseases of organs such as sight and others, just to mention an example.