Uroclasio: Indications, Contraindications, Precautions, Side Effects, Interactions and Dosage

Potassium is a mineral found in many foods and is needed for various functions in your body, especially your heartbeat.

The citric acid (Uroclasium) is a urinary alkalizing agent. It neutralizes some acid in the urine, which reduces the formation of crystals in the urine that could turn into kidney stones or aggravate gout.

Citric acid and potassium citrate are the two active substances in Uroclassium.


The combination of Uroclasio is used to treat or prevent hypokalemia (low levels of potassium in the blood). Prevent certain types of kidney stones. It can also be used for other conditions as determined by your doctor.


No use, Uroclasio si:

  • You are allergic to any of the ingredients listed.
  • You have high potassium levels in your blood, aluminum toxicity, heart failure, or severe kidney damage or problems.
  • You are taking an aldosterone blocker (e.g., spironolactone), an aluminum salt (e.g., aluminum hydroxide), a potassium-sparing diuretic (e.g., triamterene), or sucralfate.

Make sure your doctor knows if you have:

  • High levels of potassium in your blood (hyperkalemia).
  • A severe heart rhythm disorder is called ventricular fibrillation.
  • Kidney failure with sodium loss.
  • Addison’s disease (a disorder of the adrenal gland ).
  • If you are very dehydrated.
  • You should not take citric acid and potassium citrate tablets if you have problems with your esophagus, stomach, or intestines, making it difficult for you to swallow or digest pills.


Some medical conditions can interact with uroclassium. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • If you are pregnant, planning to become pregnant, or are breastfeeding.
  • If you are taking prescription or non-prescription medications, herbal preparations, or dietary supplements.
  • If you have an allergy to medicines, foods, or other substances.
  • If you have heart problems, kidney problems, difficulty swallowing, intestinal or stomach obstruction, peptic ulcer, or uncontrolled diabetes.
  • If you have diarrhea or a urinary tract infection or are dehydrated.
  • If you are on a sodium-restricted diet.
  • If you have severe burns or other tissue damage or high levels of acid or toxic substances in your blood, or if your adrenal glands are not working correctly.

Side effects

Seek emergency medical attention if you have any of these symptoms of an allergic reaction:

  • Hives
  • Difficult breathing
  • Swelling of your face, lips, tongue, or throat.

Call your doctor right away if you have any of these side effects:

  • Severe stomach pain
  • Ongoing diarrhea or vomiting
  • Black, bloody, or tarry stools.
  • Coughing up blood
  • Muscular weakness.
  • Pain or twitching
  • Numbness or tingling in your hands or feet or around your mouth.
  • Confusion.
  • Anxiety.
  • Soft spot.
  • Mood swings or feeling irritable
  • Swelling in your ankles or feet.
  • Seizure (convulsions).

Minor side effects can include:

  • Mild nausea
  • Vomiting or upset stomach
  • Mild or occasional diarrhea.
  • The appearance of a citric acid and potassium citrate tablet in your stool.

This is not a complete list of side effects and other possible occurrences. Report any unusual problem or discomfort to your doctor.


The following drugs can interact with citric acid and potassium citrate. Tell your doctor if you are using any of these:

  • Eplerenona (Inspra).
  • Candesartan (Atacand).
  • Losartan (Cozaar, Hyzaar).
  • Valsartán (Diovan).
  • Telmisartán (Micardis).
  • Quinidina (Quinaglute, Quinidex, Quin-Release).
  • An ACE inhibitor such as benazepril (Lotensin).
  • Captopril (Capoten).
  • Fosinopril (Monopril).
  • Enalapril (Vasotec).
  • Lisinopril (Prinivil, Zestril).
  • Moexipril (Univasc).
  • Prindopril (Aceon).
  • Quinapril (Accupril).
  • Ramipril ( Altace).
  • Trandolapril (Mavik).
  • Bumetanida (Bumex).
  • Chlorothiazide (Diuryl).
  • Clortalidona (Hygroton, Thalitone).
  • Ethacrynic acid (Edecrin).
  • Furosemide (Lasix).
  • Hidroclorotiazida (HCTZ, HydroDiuril).


Systemic alkalinize, Acidosis, gout (adjuvant):

Oral  (Powder): a packet dissolved in water four times a day; adjust the dose to the urinary pH Solution, 10 to 30 ml 4 times a day; adjust the amount according to urinary pH.

Administer after meals (to avoid the laxative effect) and before bed.

Give additional water after the dose, if necessary. Take after meals to minimize the laxative effect.

All dosage forms: dilute with water before administration; chill the solution before administration to improve palatability.

Powder: dilute the contents of each packet with at least 6 ounces of water.

Solution: shake well.