The Mixed Disease of Connective Tissue: Causes, Symptoms and Treatment

This rare condition has among its signs a mixture of disorders such as scleroderma, polymyositis and lupus, mainly.

It is a rare disease since the symptoms appear separately, not all at the same time, which can cause them to appear temporarily for a long time, months and even years, making their diagnosis a complicated task.

Usually the first symptom can be seen in the hands of the patient, the tips of their fingers take a whitish color and lack much sensitivity, while their fingers swell.

Because it is a disease that develops over many years, it silently attacking vital organs such as the kidneys, heart and lungs.

What causes this disease?

It is unknown the reason why this disease develops, because it has a history of immune disorders of the body, in which by mistake, the cells that defend the body from diseases, attack and destroy the organs of the body. Therefore it is an autoimmune disease.

Even to this day, this is a mystery to the scientific community, and medical researchers continue to look for the cause to achieve the identification of the proteins that cause this disorder in the immune system.

The role of the genes is not yet clear, and this is not the reason.

What are your symptoms?

  • Sensation of constant discomfort, along with a fever and very mild fatigue.
  • Swelling in the tips of the fingers.
  • Muscle pains.
  • Pains and deformation of the joints.
  • White or purple blue coloration in cold environments.
  • Reddish coloration in warm environments.
  • Skin rash.

An important risk factor.

Although this disease can occur in any age group, it generally has a greater predominance in women under 30 years of age.

Factors to watch and their complications

Pulmonary hypertension: This is the main cause of death in patients.

Alterations of the digestive tract: Abdominal pains and problems digesting food are very common.

Heart diseases: There is a greater degree to develop cardiovascular diseases in people with this condition.

Hearing loss : Loss of sense of hearing can occur in up to half of patients.

Tissue death (necrosis): Patients may develop gangrene in the fingers.

Anemia: Approximately 75% of patients have iron deficiency in the blood.

Is there any treatment?

Doctors are currently prescribing corticosteroid medications to reduce the amount and intensity of symptoms of this disease in patients, however the use of these medications can lead to health risks.

Patients with mixed connective tissue disease should take vitamin D and calcium daily to achieve greater relief of symptoms, as well as side effects on corticosteroid medications.

It is necessary to watch a doctor during the development of the disease, regular visits to the doctor’s office help to avoid other complications such as infections and osteoporosis.