Akinesia: Definition, Causes, Symptoms, Relationship with Parkinson’s Disease and Treatment

It is a medical condition in which there is an absence of normal motor functions or slowness in a person that causes a deterioration in muscle movements.

The patient suffering from akinesia does not have any normal body movement.

Anesthesia can be caused by paralysis (temporary or permanent) or being in a coma. Akinesia may interfere with all parts of the body or only with one body region.

Most antipsychotic medications cause akinesia as a side effect. In akinesia, the patient is numb, and there is a decrease in spontaneous movements.

All these side effects are similar to the apathy and slowness associated with depression or schizophrenia, and for this reason, anesthesia can often be misdiagnosed or left untreated.

Causes of akinesia

Akinesia can be caused by a series of medical ailments that resemble Parkinson’s disease. However, it is not clear what is the cause of abnormal nerve function that is related to these types of disorders, so the exact reason for the akinesia is not apparent.

Some specific medications and situations can cause akinesia. Trauma/injury to the brain’s basal ganglia can also be a causative factor.


Medications or medical conditions that cause symptoms similar to Parkinson’s disease, including akinesia, are:

Shy-Drager syndrome is a rare condition that causes deterioration in the patient’s body and produces symptoms that resemble Parkinson’s disease, including akinesia.

Medications, such as antipsychotics given for schizophrenia and severe paranoia, cause a person to have symptoms that resemble Parkinson’s disease, including akinesia.

The patient begins to experience these symptoms several weeks after taking antipsychotic medications.

Blood vessel syndromes, such as atherosclerosis and stroke, can also cause symptoms similar to Parkinson’s disease, including akinesia.

Recreational drugs, such as MPTP (synthetic heroin), cause severe Parkinson’s disease and its symptoms, including akinesia.


Acinesia means “without movement.” This is a condition in which a person experiences loss or diminution of motor functions.

The patient may experience akinesia with various medical disorders, more commonly with Parkinson’s disease. It also naturally occurs as a side effect of some medications and any trauma or injury to the brain, particularly the basal ganglia of the brain.

The most common symptoms experienced along with akinesia are apathy, in which the patient is indifferent to everything and everyone, and there is no interest in the environment.

In akinesia, there is also a significant decrease in the patient’s movements, especially in spontaneous movements and reflexes.

In akinesia, the patient’s face also seems fixed and expressionless.

Patients suffering from akinesia rarely blink; their eyelids and the patient’s speech are monotonous with no modulation.

The patient also tires easily when told to do repetitive movements. In addition, the patient can not perform everyday tasks that require simultaneous and sequential actions.

In severe cases of akinesia, the patient may be wholly immobile or disabled.

Treatment depends on the disease, which is causing akinesia, and the severity. Patients should understand that akinesia is occurring due to some other diagnosed medical problem and that it is occurring as a complication or a side effect.

Akinesia crisis due to Parkinson’s disease:

Patients with Parkinson’s disease may also experience an akinesia crisis where the patient experiences a severe disability in moving.

This condition occurs when a patient undergoes prolonged therapy consisting of L-DOPA or Levo-dihydroxyphenylalanine. This condition is relieved by administering intravenous iron in the Ferro-ferry complex, with the patients recovering a significant capacity for movement again.

The dose administered decides the amount of akinesia crisis relief. The greater the quantity, the more significant the improvement, but it is essential to first assess the patient’s condition and the severity of the akinesia crisis before deciding on the dose.

After this, the iron administration must be carefully reduced, and its extraction must be carefully administered and monitored. If there is an inadequate withdrawal, it can trigger an akinesia crisis’s relapse.

Treatment for akinesia

Treatment varies and depends on the underlying medical condition that causes akinesia and, in general, is similar to the treatment for Parkinson’s disease.

If a person is bedridden for several months, that person may develop akinesia, especially in the lower extremities. In such cases, physical therapy is the main line of treatment to recover strength and use of the legs.

The patient should consult a doctor specializing in this type of movement disorder.