Index
Its active principle is desloratadine and relieves symptoms associated with allergic rhinitides, such as swelling of the nasal passages induced by an allergy.
Among those allergies, we find, for example, hay fever or allergy to dust mites.
Symptoms include constant sneezing, persistent runny or nasal itching, itching of the palate, redness of the eyes, or tearing.
This medication is also used to relieve symptoms associated with hives, a skin disease caused by allergies whose symptoms include itching and skin lesions.
The effect for the relief of these symptoms lasts for a day and helps to develop the patient’s daily activities and to recover the regular periods of sleep.
Chemical formula
- C19H19N2Cl.
- 8-cloro-6,11-dihidro-11-(4-piperdinilideno)- 5Hbenzo[5,6]ciclohepta[1,2-b]piridin.
Presentation
- Tablet in the presentation of 5mg of desloratadine.
- Syrup with a concentration of 0.5 mg/ml of desloratadine.
Indications
Desalex is indicated for treating symptoms associated with allergic, dermatological conditions such as chronic idiopathic urticaria and atopic dermatitis, with symptoms such as pruritus and wheals.
Allergic and respiratory diseases such as intermittent allergic rhinitis, intermittent, persistent rhinitis, and asthma concomitant symptoms associated with sneezing, secretions, itching, congestion, and nasal blockage.
Moreover, tearing, redness of the eyes and ocular itching, also pruritus on the palate, and cough.
Mechanism of action
Desalex is a long-acting drug, without sedative effects, with an aggressive and selective action of peripheral histamine H1 receptors.
The Desalex works as an antiallergic, an antihistamine, and an anti-inflammatory.
Dose
Syrup: The dose to be given in children from 6 to 11 years of age is 5ml (2.5mg) once a day and in children between 2 and 5 years of age in doses of 2.5ml ( 1,25mg) only once a day.
In children from 6 months to 1 year of age: in doses of 2ml (1mg) only once a day. For adults and adolescents (over 12 years of age), a 10ml (5mg) dose should be administered only once daily.
Tablets: In adults and adolescents (over 12 years of age), the dose of a 5mg tablet should be given once a day.
Side effects
Very few cases of adverse effects have been reported currently due to the use of Desalex; among them are the severe allergic reactions such as:
She was breathing with wheezing, difficulty breathing, itching, skin lesions, swelling, and skin rashes.
Palpitations have also been rarely reported, with increased heart rate, stomach pain, vomiting, nausea, seizures, muscle pain, gastric discomfort, and diarrhea.
Drowsiness, dizziness, difficulty sleeping, hallucinations, inflammation of the liver, and laboratory alteration in liver function tests.
Warnings and contraindications
Do not give Desalex in case of allergy (hypersensitive) to the active substance:
Desloratadine or any substances that make up the pharmaceutical presentation of the drug.
Symptoms of dyslexia allergy may include:
- Episodes of asthma attacks, breathing difficulties accompanied by audible whistles or breathing very fast.
- A more or less violent swelling may develop on the face, lips, tongue, or other body parts. This swelling is especially critical if it affects the vocal cords.
- It can develop hives, itching, and skin rash.
- An anaphylactic shock may eventually occur with loss of consciousness, pallor, and sweating, among other symptoms.
- Special care should be taken with the administration of Desalex if you suffer from or have impaired renal function.
However, since there is no clinical information about the use of Desalex during pregnancy, safety has not been established.
Therefore, the Desalex should not be administered during pregnancy unless the doctor considers it, taking into account the product’s potential benefits on the risks.
Desalex is excreted in breast milk, which is not recommended during breastfeeding.
Interactions
The clinical works on Desalex and other medicines have not presented evidence of drug interactions of clinical relevance.
