Desalex: Formula, Presentation, Indications, Dosage, Side Effects, Warnings and Indications

Its active principle is desloratadine and relieves symptoms that are associated with allergic rhinitis, such as swelling of the nasal passages induced by an allergy.

Among those allergies we find, for example; hay fever or allergy to dust mites .

Symptoms include constant sneezing, persistent runny or nasal itching, itching of the palate, redness of the eyes or tearing .

This medication is also used for the relief of symptoms associated with hives , which is a skin disease caused by allergies and whose symptoms include itching and skin lesions.

The effect for the relief of these symptoms lasts for a day and helps to develop the daily activities of the patient and to recover the normal periods of sleep.

Chemical formula

  • C19H19N2Cl.
  • 8-cloro-6,11-dihidro-11-(4-piperdinilideno)- 5Hbenzo[5,6]ciclohepta[1,2-b]piridin.


  • Tablet in presentation of 5mg of desloratadine.
  • Syrup with a concentration of 0.5 mg / ml of desloratadine.


Desalex is indicated for the treatment of symptoms associated with dermatological allergic conditions such as chronic idiopathic urticaria and others such as atopic dermatitis, with symptoms such as pruritus and wheals.

Allergic and respiratory diseases such as allergic rhinitis intermittent, persistent allergic rhinitis and asthma concomitant symptoms associated with as sneezing, secretions, itching, congestion and nasal blockage.

And tearing, redness of the eyes and ocular itching, also pruritus on the palate and cough.

Mechanism of action

Desalex is a long-acting drug, without sedative effects, with an antagonistic and selective action of peripheral histamine H1 receptors.

The Desalex works as an antiallergic, an antihistamine and an anti-inflammatory.


Syrup: The dose to be given in children from 6 to 11 years of age is 5ml (2.5mg) once a day and in children between 2 and 5 years of age in doses of 2.5ml ( 1,25mg) only once a day.

In children from 6 months to 1 year of age : in doses of 2ml (1mg) only once a day. Adults and adolescents (over 12 years of age), a dose of 10ml (5mg) should be administered only once a day.

Tablets: In adults and adolescents (over 12 years of age), the dose of a 5mg tablet should be given once a day.

Side effects

Very few cases of adverse effects have been reported currently, due to the use of Desalex, among them are the serious allergic reactions such as:

Breathing with wheezing, difficulty breathing, itching, skin lesions, swelling and skin rashes.

Palpitations have also been reported very rarely, with increased heart rate, stomach pain, vomiting, nausea, seizures, muscle pain, gastric discomfort and diarrhea.

Drowsiness, dizziness, difficulty sleeping, hallucinations, inflammation of the liver and laboratory alteration in liver function tests.

Warnings and contraindications

Do not give Desalex in case of allergy (hypersensitive) to the active substance:

Desloratadine or any of the substances that make up the pharmaceutical presentation of the drug.

Symptoms of dyslexia allergy may include:

  • Episodes of asthma attacks, with breathing difficulties, breathing accompanied by audible whistles or breathing very fast.
  • A more or less violent swelling may develop on the face, lips, tongue or some other part of the body. This swelling is especially critical if it affects the vocal cords.
  • It can develop hives , itching and skin rash.
  • An anaphylactic shock may eventually occur with loss of consciousness, pallor, sweating, among other symptoms.
  • Special care should be taken with the administration of Desalex, if you suffer from or have suffered from impaired renal function.

However, since there is no clinical information about the use of Desalex during pregnancy, safety has not been established.

Therefore, the Desalex should not be administered during pregnancy, unless the doctor considers it, taking into account the potential benefits of the product on the risks.

Desalex is excreted in breast milk, which is not recommended during breastfeeding.


The clinical works carried out on the use of Desalex, together with other medicines, have not presented evidence of drug interactions of clinical relevance.

No effects have been observed in the consumption of food, alcohol or grapefruit juice on interactions or changes in the availability of Desalex for the patient.